Methodological problems in bilateral electrodermal research.

Since the beginning of the 1970's, bilaterally recorded electrodermal activity (EDA) has generated a significant amount of research. It has been used in studies of hemispheric asymmetry, as well as in psychiatry as an indicator of left and right hemisphere activity. However an examination of the various studies which have utilized this technique does not show an overall consensus, and the results, as well as their interpretations, are often contradictory. These difficulties can partially be explained in terms of problems of methodology and interpretation. The aim of this paper is to review the methodological considerations, which have been grouped into 3 categories: stimulus specificity; the selection of subjects; and the measurement and interpretation of EDA.