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简易小儿磁共振成像制剂的应用:日本的一项多中心研究

Application of simple preparation for pediatric magnetic resonance imaging: a multicenter study in Japan.

作者信息

Sawada Naomi, Kawada Jun-Ichi, Kito Shuichi, Takeo Toshiki, Narita Hajime, Fukushima Mai, Masuda Yu, Mitsumatsu Takamasa, Kawano Yoshihiko, Sakaguchi Yoko, Nishio Nobuhiro, Kidokoro Hiroyuki, Sato Yoshiaki, Takahashi Yoshiyuki

机构信息

Nagoya University Graduate School of Medicine, Nagoya, Japan.

Department of Pediatrics, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.

出版信息

Pediatr Radiol. 2025 May;55(5):976-982. doi: 10.1007/s00247-025-06194-6. Epub 2025 Feb 20.

DOI:10.1007/s00247-025-06194-6
PMID:39976708
Abstract

BACKGROUND

Sedation with anesthetic medication is often required to perform magnetic resonance imaging (MRI) scans in young children. However, sedation involves risks, particularly respiratory depression. Therefore, it is crucial to explore methods enabling young children to undergo MRI scans without sedation. Additionally, developing MRI preparation techniques for young children that are feasible in general hospitals-without specialized staff or equipment-has become increasingly desirable.

OBJECTIVE

This study aimed to develop a straightforward preparation method for pediatric MRI scans and evaluate its effectiveness.

MATERIALS AND METHODS

We prospectively enrolled 43 children ages 4-6 years (mean age, 5.8 years) who were scheduled for MRI scans at five general hospitals. Patients requiring urgent MRI scans were excluded from the study. We provided simple preparations created by child life specialists to help children and guardians easily understand MRI scans. A historical control group comprised 44 consecutive children, ages 4-6 years, who had undergone MRI scans before this preparatory intervention was introduced.

RESULTS

Following the introduction of the preparation, a significantly higher percentage of patients attempted MRI scans without sedation than historical controls (60.5% vs. 15.9%, P < 0.001). Additionally, the success rate of performing MRI without sedation increased markedly (53.5% vs. 13.6%, P < 0.001).

CONCLUSION

Introducing the simple preparation allowed for more successful non-sedated MRI scans in children ages 4-6 years. This preparation may contribute to higher rates of successful non-sedated MRIs among children in general hospitals, even in settings lacking specialized staff or equipment.

摘要

背景

在对幼儿进行磁共振成像(MRI)扫描时,通常需要使用麻醉药物进行镇静。然而,镇静存在风险,尤其是呼吸抑制。因此,探索使幼儿无需镇静即可接受MRI扫描的方法至关重要。此外,开发在普通医院(无需专业人员或设备)可行的幼儿MRI准备技术变得越来越必要。

目的

本研究旨在开发一种简单的儿科MRI扫描准备方法并评估其有效性。

材料与方法

我们前瞻性地招募了43名年龄在4至6岁(平均年龄5.8岁)、计划在五家普通医院进行MRI扫描的儿童。需要紧急MRI扫描的患者被排除在研究之外。我们提供了由儿童生活专家创建的简单准备措施,以帮助儿童和监护人轻松理解MRI扫描。一个历史对照组由44名年龄在4至6岁、在引入这种准备干预措施之前接受过MRI扫描的连续儿童组成。

结果

引入准备措施后,尝试不使用镇静剂进行MRI扫描的患者比例显著高于历史对照组(60.5%对15.9%,P<0.001)。此外,不使用镇静剂进行MRI扫描的成功率显著提高(53.5%对13.6%,P<0.001)。

结论

引入这种简单的准备措施可使4至6岁儿童更成功地进行非镇静MRI扫描。这种准备措施可能有助于提高普通医院儿童非镇静MRI扫描的成功率,即使在缺乏专业人员或设备的情况下也是如此。

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本文引用的文献

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Pediatr Radiol. 2023 Jun;53(7):1476-1484. doi: 10.1007/s00247-023-05647-0. Epub 2023 Apr 3.
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Strategies to perform magnetic resonance imaging in infants and young children without sedation.无镇静状态下对婴儿和幼儿进行磁共振成像的策略。
Pediatr Radiol. 2022 Feb;52(2):374-381. doi: 10.1007/s00247-021-05062-3. Epub 2021 Apr 8.
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Pediatrics. 2021 Jan;147(1). doi: 10.1542/peds.2020-040261.
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Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures.儿科患者镇静诊断和治疗程序前、中、后监测和管理指南。
Pediatrics. 2019 Jun;143(6). doi: 10.1542/peds.2019-1000.
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Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children.儿童急诊科程序性镇静不良事件的危险因素
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High success rates of sedation-free brain MRI scanning in young children using simple subject preparation protocols with and without a commercial mock scanner--the Diabetes Research in Children Network (DirecNet) experience.使用有和没有商用模拟扫描仪的简单受检者准备方案,在幼儿中实现无镇静脑 MRI 扫描的高成功率:糖尿病儿研究网络(DirecNet)经验。
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