Bond Elizabeth C, Cochran Grant, Bulleit Clark H, Poehlein Emily, Green Cynthia L, Wittstein Jocelyn R
Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, North Carolina.
Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
J Knee Surg. 2025 Jul;38(9):463-468. doi: 10.1055/a-2542-2639. Epub 2025 Feb 20.
Varus-producing distal femoral osteotomy (DFO) is an established procedure to correct genu valgum in patients with osteoarthritis and gait abnormalities. DFO has also been proposed for the treatment of patellar instability in patients with valgus alignment. However, it is not known how DFO affects parameters associated with patellar instability. This study evaluated radiographic changes after DFO with variable degrees of correction on six cadaveric knees, with the hypothesis that improving mechanical alignment would improve radiographic parameters related to patellar instability. Controlled laboratory is the study design. Six lower-limb cadaveric specimens were obtained after approval by the Institutional Review Board. A lateral opening wedge DFO was performed on each specimen with correction blocks of 6, 10, and 14 mm. The mechanical axis, tibiofemoral angle (mTFA), distal femoral angle (mDFA), Caton Deschamps index (CDI), insall salvati index (ISI), tibial tubercle to trochlear groove distance (TT-TG), and patellofemoral congruence angle (PFCA) were measured on computed tomography (CT) scans at baseline and after each correction block. At baseline, a mean varus alignment of the limbs was observed (mTFA: 2.7 ± 2.8 degrees, mDFA: 87.6 ± 1.0 degrees). The baseline patellar height was normal (CDI: 0.9 ± 0.2, ISI: 1.0 ± 0.1). Statistically significant decreases in mechanical axis and TT-TG distance and increases in mDFA and mFTA were found with increasing block size. The TT-TG distance was decreased by -1.6 mm (95% confidence interval [CI]: -2.27 to -0.86), -3.8 mm (95% CI: -4.8 to -2.8), and -4.0 mm (95% CI: -5.4 to -2.7) with a 6, 10, and 14 mm block, respectively. No differences were observed in patellar height when measured with CDI or ISI after any block size. In a cadaveric model, DFO significantly affects the mechanical axis and TT-TG distance. Specifically, this study found a mean decrease in TT-TG of -3.8 mm when performing a 10 mm opening wedge osteotomy. No changes in patellar height were observed.
股骨远端内翻截骨术(DFO)是一种成熟的手术方法,用于矫正骨关节炎和步态异常患者的膝外翻。DFO也被提议用于治疗外翻畸形患者的髌骨不稳定。然而,尚不清楚DFO如何影响与髌骨不稳定相关的参数。本研究评估了六具尸体膝关节在不同程度矫正的DFO后的影像学变化,假设改善机械对线将改善与髌骨不稳定相关的影像学参数。本研究采用对照实验室设计。经机构审查委员会批准后,获取了六个下肢尸体标本。对每个标本进行外侧开口楔形DFO,使用6、10和14毫米的矫正块。在基线时以及每个矫正块使用后,通过计算机断层扫描(CT)测量机械轴、胫股角(mTFA)、股骨远端角(mDFA)、卡顿·德尚指数(CDI)、英萨尔·萨尔瓦蒂指数(ISI)、胫骨结节至滑车沟距离(TT-TG)和髌股适合角(PFCA)。在基线时,观察到肢体平均呈内翻对线(mTFA:2.7±2.8度,mDFA:87.6±1.0度)。基线时髌骨高度正常(CDI:0.9±0.2,ISI:1.0±0.1)。随着矫正块尺寸增加,发现机械轴和TT-TG距离有统计学意义的减小,mDFA和mFTA增加。使用6毫米、10毫米和14毫米的矫正块时,TT-TG距离分别减少了-1.6毫米(95%置信区间[CI]:-2.27至-0.86)、-3.8毫米(95%CI:-4.8至-2.8)和-4.0毫米(95%CI:-5.4至-2.7)。在任何矫正块尺寸后,用CDI或ISI测量时,髌骨高度均未观察到差异。在尸体模型中,DFO显著影响机械轴和TT-TG距离。具体而言,本研究发现,进行10毫米开口楔形截骨术时,TT-TG平均减少3.8毫米。未观察到髌骨高度变化。