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[用于抗癌化疗的完全植入式导管。法国325例经验]

[Completely implantable catheters for anticancer chemotherapy. A French experience of 325 cases].

作者信息

Champault G

出版信息

J Chir (Paris). 1985 Apr;122(4):269-72.

PMID:3997995
Abstract

Three hundred and twenty five implantable catheters (PAC) were used in the treatment of 319 patients with neoplastic disease in 21 French centers. Two hundred and sixty three were inserted in central venous position, 43 in hepatic artery and 11 were intraportal. There were no failures at the time of insertion nor any deaths imputable to the method. Whilst the mean duration of use was 182 days, 72 catheters remain patent after one year of use or more. The risk of obstruction is 3,6% : 1,5% for I.V. sites and 13,9% in intra-arterial because internal caliber are smaller. There were 2,4%, of cases of skin leakage or necrosis and sepsis rate was 2,7%, more frequent er after percutaneous insertion. These result justify the use of this device in long term chemotherapy.

摘要

法国21个中心使用325根可植入导管(PAC)治疗了319例肿瘤疾病患者。263根插入中心静脉位置,43根插入肝动脉,11根插入门静脉。插入时无失败情况,也没有因该方法导致的死亡。虽然平均使用时间为182天,但72根导管在使用一年或更长时间后仍保持通畅。阻塞风险为3.6%:静脉部位为1.5%,动脉内为13.9%,因为内部管径较小。有2.4%的病例出现皮肤渗漏或坏死,败血症发生率为2.7%,经皮插入后更常见。这些结果证明了该装置在长期化疗中的应用价值。

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