Meltzer Andrew C, Morrison Callen, Loganathan Aditya, Shahamatdar Soroush, Moon Alice, Heidish Ryan, Makutonin Michael, Ma Yan, Li Runjia, Cooper Ziva D
Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC.
Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC.
Ann Emerg Med. 2025 Jun;85(6):521-525. doi: 10.1016/j.annemergmed.2025.01.008. Epub 2025 Feb 20.
Cannabinoid hyperemesis syndrome is an underrecognized condition associated with recurrent vomiting and abdominal pain in individuals with prolonged cannabis use. This study used an internet-based survey targeting individuals with self-reported cannabinoid hyperemesis syndrome to assess the burden of disease and to examine associations between heavy cannabis use, early initiation of cannabis use, and cannabinoid hyperemesis syndrome episode frequency. A total of 1,052 participants were included, with the majority reporting frequent cannabis use and significant health care utilization, including emergency department visits and hospitalizations. This study highlights the substantial disease burden associated with cannabinoid hyperemesis syndrome in an online support group cohort and underscores the possible risks of heavy daily cannabis use and of use starting in adolescence. Future studies on heavy cannabis users are necessary to further elucidate cannabinoid hyperemesis syndrome and its link to daily cannabis use and the dangers of heavy use in adolescence.
大麻素呕吐综合征是一种未被充分认识的病症，与长期使用大麻的个体反复呕吐和腹痛有关。本研究通过一项针对自我报告患有大麻素呕吐综合征的个体的基于互联网的调查，来评估疾病负担，并研究大量使用大麻、早期开始使用大麻与大麻素呕吐综合征发作频率之间的关联。总共纳入了1052名参与者，大多数人报告频繁使用大麻且有大量医疗保健利用情况，包括急诊就诊和住院治疗。本研究突出了在线支持群体队列中与大麻素呕吐综合征相关的巨大疾病负担，并强调了每日大量使用大麻以及青少年时期开始使用大麻的潜在风险。未来有必要对大量使用大麻的人群进行研究，以进一步阐明大麻素呕吐综合征及其与每日使用大麻的关系以及青少年大量使用大麻的危害。
