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梅尼埃病综述——来自新西兰的已发表MRI、耳声发射和新耳石理论的反映

A review of Meniere's disease - reflection of published MRI, ECochG and newer otoconial theory from Aotearoa New Zealand.

作者信息

Quick Mark E, Bird Philip A

机构信息

Department of Otolaryngology Head and Neck Surgery and Audiology, Christchurch Hospital, Christchurch, Aotearoa New Zealand.

Department of Surgery, University of Otago, Christchurch, New Zealand.

出版信息

J R Soc N Z. 2024 Jul 31;55(3):441-450. doi: 10.1080/03036758.2024.2381731. eCollection 2025.

Abstract

Vertigo, or the symptom of an hallucination of motion, is usually caused by disorders of the inner ear. Buried in the bone of the otic capsule, the inner ear is the most difficult human sensory organ to image and investigate. As an inner ear disorder, Meniere's disease (MD) is characterised as recurrent vertiginous attacks, fluctuating hearing loss which can be progressive, tinnitus and aural fullness. Post-mortem studies, and now MRI inner ear imaging, show an excess of endolymph or endolymphatic hydrops (ELH) which has been to usually commence in the cochlea. However, the cause of the initial hydrops is still debated. This paper reflects on the research published in Ōtautahi Christchurch, Aotearoa New Zealand. There is evidence from post-mortem studies, electrophysiological test, and some inner ear imaging that endolymphatic obstruction from clumps of detached saccular otoconia may be a cause of MD.

摘要

眩晕,即运动幻觉症状,通常由内耳疾病引起。内耳深藏于听囊骨内,是最难进行成像和研究的人体感觉器官。作为一种内耳疾病,梅尼埃病(MD)的特征是反复发作的眩晕、波动性听力损失(可能呈进行性)、耳鸣和耳胀满感。尸检研究以及现在的内耳MRI成像显示,内淋巴过多或内淋巴积水(ELH)通常始于耳蜗。然而,最初积水的原因仍存在争议。本文对在新西兰奥特亚罗瓦克赖斯特彻奇发表的研究进行了反思。尸检研究、电生理测试以及一些内耳成像的证据表明,分离的球囊耳石团块导致的内淋巴阻塞可能是梅尼埃病的一个病因。

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本文引用的文献

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Ductus Reuniens and Its Possible Role in Menière's Disease.集合管及其在梅尼埃病中的可能作用。
Otol Neurotol. 2021 Dec 1;42(10):1585-1593. doi: 10.1097/MAO.0000000000003352.
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A New Theory for Ménière's Disease: Detached Saccular Otoconia.梅尼埃病的一种新理论:球囊耳石脱离。
Otolaryngol Head Neck Surg. 2017 Feb;156(2):350-352. doi: 10.1177/0194599816675843. Epub 2016 Nov 14.

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