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内固定联合自体软骨细胞植入治疗合并软骨损伤的胫骨平台骨折：一例报告

Combined internal fixation and autologous chondrocyte implantation for tibial plateau fracture concomitant with cartilage injury: a case report.

作者信息

Sogi Yasuhito, Ohnuma Masahiro, Kunii Tomonori, Takahashi Atsushi, Aizawa Toshimi

机构信息

Department of Orthopaedic Surgery, Japanese Red Cross Sendai Hospital, 2-43-3 Yagiyamahoncho, Taihaku-ku, Sendai 982-8501, Japan.

Department of Orthopaedic Surgery, Tohoku Rosai Hospital, 4-3-21 Dainohara, Aoba-ku, Sendai 981-8563, Japan.

出版信息

J Surg Case Rep. 2025 Feb 21;2025(2):rjaf078. doi: 10.1093/jscr/rjaf078. eCollection 2025 Feb.

DOI:10.1093/jscr/rjaf078
PMID:39989730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11844754/
Abstract

This is the first report of tibia plateau fracture (TPF) concomitant with a large cartilage injury, which was treated with consecutive procedures comprising internal fixation and autologous chondrocyte implantation (ACI). A 49-year-old male patient was diagnosed with a medial tibial plateau fracture concomitant with a large medial femoral condyle cartilage injury. The patient underwent internal fixation and ACI at a 4-week interval. One year after the surgery, he could resume daily activities and sports. Magnetic resonance imaging and arthroscopic findings showed that the injured cartilage was covered by hyaline cartilage-like tissue. TPF concomitant with large cartilage injury can be treated with consecutive internal fixation and ACI procedures, shortening the overall treatment period and favorable outcomes.

摘要

这是关于胫骨平台骨折（TPF）合并大面积软骨损伤的首例报告，该病例采用了包括内固定和自体软骨细胞植入（ACI）在内的连续手术进行治疗。一名49岁男性患者被诊断为胫骨内侧平台骨折合并股骨内侧髁大面积软骨损伤。患者在间隔4周后接受了内固定和ACI手术。术后一年，他能够恢复日常活动和运动。磁共振成像和关节镜检查结果显示，损伤的软骨被透明软骨样组织覆盖。TPF合并大面积软骨损伤可通过连续的内固定和ACI手术进行治疗，缩短了整体治疗周期并取得了良好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/c35fe12bec22/rjaf078f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/f79bceae9c11/rjaf078f1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/aae420b00562/rjaf078f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/08137fd6deb5/rjaf078f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/5eb5121c4e2b/rjaf078f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/c35fe12bec22/rjaf078f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/f79bceae9c11/rjaf078f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/7a4ec9fbe201/rjaf078f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/cd8c2cdfa84f/rjaf078f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/aae420b00562/rjaf078f4.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/11844754/c35fe12bec22/rjaf078f7.jpg

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本文引用的文献

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Long-Term Outcomes of Arthroscopically Verified Focal Cartilage Lesions in the Knee: A 19-Year Multicenter Follow-up with Patient-Reported Outcomes.关节镜下证实膝关节局灶性软骨病变的长期结果：一项 19 年多中心随访的患者报告结局。
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关节内出血加速固定膝关节模型大鼠的软骨退变。
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