Qing Peidong, Xie Shiming, Feng Chaoqun, Xu Hongda, Zhao Shengxin, Zhang Lei, Deng Haitao, Wang Yehui, Hu Youpeng
Mianyang Orthopedic Hospital, Mianyang, China.
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Surg. 2025 Feb 10;12:1472886. doi: 10.3389/fsurg.2025.1472886. eCollection 2025.
Gout is a common disease; however, a gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date.
We report the case of a 70-year-old female who presented with lower back pain, right radicular pain, and numbness in the perineal area. Magnetic resonance imaging and computed tomography scans revealed a calcified intradural lesion at the L3 level. The diagnosis of the lesion was not definitive because the patient had no history of gout or manifestations of systemic gout. Surgical removal of the intradural lesion followed by pathological examination confirmed gouty tophi. The postoperative recovery was good, and the patient experienced substantial relief from pain and numbness.
This is the third documented case of gout tophi occurring within the spinal dura. In a literature review, it was found that none of these three patients with intradural gouty tophi had systemic gout manifestations or hyperuricemia, which is a crucial finding. As it is challenging to diagnose intradural gout, awareness among physicians must be increased to optimize the treatment of, and outcomes for, these patients.
痛风是一种常见疾病;然而,脊髓硬脊膜内出现痛风石极为罕见,迄今为止仅报道过两例。
我们报告一例70岁女性患者,其表现为下背部疼痛、右下肢放射性疼痛及会阴区麻木。磁共振成像和计算机断层扫描显示L3水平有一硬脊膜内钙化病变。由于患者无痛风病史或全身性痛风表现,该病变的诊断尚不明确。手术切除硬脊膜内病变并进行病理检查确诊为痛风石。术后恢复良好,患者疼痛和麻木症状明显缓解。
这是第三例有文献记载的脊髓硬脊膜内痛风石病例。在文献回顾中发现,这三例硬脊膜内痛风石患者均无全身性痛风表现或高尿酸血症,这是一个关键发现。由于硬脊膜内痛风的诊断具有挑战性,必须提高医生的认识,以优化这些患者的治疗及预后。