No allergy, but mast cells are involved: MRGPRX2 in chronic inflammatory skin diseases.
作者信息
Metz Martin
机构信息
Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany.
出版信息
J Eur Acad Dermatol Venereol. 2025 Mar;39(3):451-452. doi: 10.1111/jdv.20541.
Abstract
摘要
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No allergy, but mast cells are involved: MRGPRX2 in chronic inflammatory skin diseases.无过敏反应，但肥大细胞参与其中：慢性炎症性皮肤病中的MRGPRX2
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本文引用的文献
1
Mast Cells and Mas-related G Protein-coupled Receptor X2: Itching for Novel Pathophysiological Insights to Clinical Relevance.肥大细胞和 Mas 相关 G 蛋白偶联受体 X2：渴望为临床相关性提供新的病理生理学见解。
Curr Allergy Asthma Rep. 2024 Nov 25;25(1):5. doi: 10.1007/s11882-024-01183-5.
2
Beyond the classic players: Mas-related G protein-coupled receptor member X2 role in pruritus and skin diseases.超越经典参与者：Mas相关G蛋白偶联受体成员X2在瘙痒和皮肤病中的作用
J Eur Acad Dermatol Venereol. 2025 Mar;39(3):476-486. doi: 10.1111/jdv.20249. Epub 2024 Jul 23.
3
Mas-related G protein-coupled receptor X2 and its activators in dermatologic allergies.Mas 相关 G 蛋白偶联受体 X2 及其在皮肤过敏中的激活剂。
J Allergy Clin Immunol. 2021 Feb;147(2):456-469. doi: 10.1016/j.jaci.2020.08.027. Epub 2020 Oct 15.
4
Mast Cells in Inflammation and Disease: Recent Progress and Ongoing Concerns.肥大细胞在炎症和疾病中的作用：最新进展和持续关注。
Annu Rev Immunol. 2020 Apr 26;38:49-77. doi: 10.1146/annurev-immunol-071719-094903.
5
Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions.鉴定对伪过敏性药物反应至关重要的肥大细胞特异性受体。
Nature. 2015 Mar 12;519(7542):237-41. doi: 10.1038/nature14022. Epub 2014 Dec 17.
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