Lawson Kim, Hall Jennifer, Bourne Tom, Bottomley Cecilia
Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
UCL EGA Institute for Women's Health, Reproductive Health Research Department, London, UK.
Eur J Obstet Gynecol Reprod Biol. 2025 Apr;307:259-264. doi: 10.1016/j.ejogrb.2025.02.004. Epub 2025 Feb 5.
To explore how women, understand, interpret and use a validated individualised early pregnancy outcome prediction score tool.
Qualitative interview study nested within a larger quantitative randomised controlled trial (RCT) within the Early Pregnancy Unit of a London teaching hospital. Women with an ultrasound diagnosis of an early intrauterine pregnancy of uncertain viability (PUV) were randomised to receive a validated outcome prediction score or routine care. Those who received the prediction were invited to interview. Thematic analysis was conducted with a focus on women's experiences of receiving the prediction model. The study was complete when no further themes emerged.
Eleven interviews were completed. Five themes emerged from the data: 1) Credibility, 2) Setting Expectations, 3) Sharing, 4) Reflecting and 5) Risks. Scientific development of the tool and delivery by a healthcare professional lent credibility. Women mostly found the prediction tool helpful in anticipating and preparing for the actual outcome. Women largely did not share their prediction outside immediate family. Where women perceived that the tool did not take sufficient account of individual previous experience, less value was attributed. Women also believed in a potential psychological risk from a high prediction of viability being followed by a poor outcome.
This study presents a nuanced understanding of women's use of an outcome prediction tool, which is not found from standard quantitative data. Recognising how women rationalise and use information is as important as statistical performance of a tool when implementing supportive care interventions. Whilst the results give better understanding in cases of PUV, it is not known whether the findings can be generalised to other early pregnancy scenarios.
探讨女性如何理解、解读和使用经过验证的个体化早期妊娠结局预测评分工具。
定性访谈研究,嵌套于伦敦一家教学医院早期妊娠科的一项更大规模的定量随机对照试验(RCT)中。超声诊断为早期宫内妊娠且存活情况不确定(PUV)的女性被随机分配接受经过验证的结局预测评分或常规护理。接受预测的女性受邀参加访谈。进行了主题分析,重点关注女性接受预测模型的经历。当不再出现新的主题时,研究结束。
完成了11次访谈。数据中出现了五个主题:1)可信度,2)设定期望,3)分享,4)反思和5)风险。该工具的科学开发以及由医疗保健专业人员提供使其具有可信度。女性大多发现预测工具有助于预测和为实际结局做准备。女性大多不会在直系亲属之外分享她们的预测结果。当女性认为该工具没有充分考虑个人既往经历时,其价值就会被低估。女性还认为,高存活预测之后紧接着不良结局可能存在心理风险。
本研究对女性使用结局预测工具的情况进行了细致入微的理解,这是标准定量数据无法体现的。在实施支持性护理干预措施时,认识女性如何使信息合理化并加以使用与工具的统计性能同样重要。虽然研究结果能更好地理解PUV情况,但尚不清楚这些发现能否推广到其他早期妊娠情形。