Zou Chen, Liu Wei, Chang Qing, Xuan Yi, Zhou Yao, Tang Nuo, Wang Min
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Retina. 2025 May 1;45(5):901-907. doi: 10.1097/IAE.0000000000004406.
To study the imaging findings of ultrawide-field swept source optical coherence tomography angiography (ss-OCTA) and its advantages with respect to ultrawide-field fundus photography (FP) in the precise diagnosis of diabetic retinopathy (DR), and to reveal its applications in DR.
The imaging findings of microangiopathy in ultrawide-field ss-OCTA and ultrawide-field FP from patients with DR were retrospectively analyzed, and the differences between the two methods were assessed. In addition, the grade of DR based on the imaging findings of the two modalities was determined and compared.
Ultra-widefield ss-OCTA clearly revealed various occult retinal microvascular lesions in patients with DR over a detection range, which was similar to ultrawide-field FP. Significantly more retinal microangiopathy were detected and more eyes were given a worse DR grade with ultrawide-field ss-OCTA than those with ultrawide-field FP.
Ultrawide-field ss-OCTA is more able to detect retinal microangiopathy compared with ultrawide-field FP and is contributive in the precise diagnosis of DR. Ultrawide-field ss-OCTA has substantial applicability in the precise diagnosis of DR, especially when ultrawide-field fundus fluorescence angiography is unavailable.
研究超广角扫频源光学相干断层扫描血管造影（ss-OCTA）的影像学表现及其在糖尿病视网膜病变（DR）精确诊断中相对于超广角眼底摄影（FP）的优势，并揭示其在DR中的应用。
回顾性分析DR患者超广角ss-OCTA和超广角FP微血管病变的影像学表现，并评估两种方法之间的差异。此外，根据两种检查方式的影像学表现确定并比较DR的分级。
超广角ss-OCTA在检测范围内清晰显示了DR患者各种隐匿性视网膜微血管病变，这与超广角FP相似。与超广角FP相比，超广角ss-OCTA检测到的视网膜微血管病变明显更多，且更多眼睛的DR分级更差。
与超广角FP相比，超广角ss-OCTA更能检测视网膜微血管病变，有助于DR的精确诊断。超广角ss-OCTA在DR的精确诊断中具有重要的适用性，尤其是在无法进行超广角眼底荧光血管造影时。
