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残疾人群中的抑郁症:尼泊尔一项基于社区的横断面研究。

Depression among individuals with disabilities: a community-based cross-sectional study in Nepal.

作者信息

Ghimire Apekshya, Mishra Durga Kumari Khadka

机构信息

Department of Public Health, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal

Department of Public Health, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal.

出版信息

BMJ Open. 2025 Feb 25;15(2):e082955. doi: 10.1136/bmjopen-2023-082955.

Abstract

OBJECTIVE

To assess the prevalence of depression and its associated factors among individuals with disabilities.

DESIGN

Cross-sectional study.

SETTING

Community-based study conducted in Ilam municipality, Nepal, from October to November 2019.

PARTICIPANTS

The study was conducted among 164 people with physical, hearing and vision-related disabilities. Participants were selected through a simple random sampling method using the sampling frame obtained from Ilam municipality.

MAIN OUTCOME MEASURE

Depression and its associated factors among people with disabilities. Depression was assessed via a validated Nepali version of the Hospital Anxiety and Depression Scale. Data collection was based on a pretested structured questionnaire.

RESULTS

The prevalence of depression was 39% among people with disabilities, and 29.9% of the respondents were in borderline depression. In an unadjusted analysis, depression was significantly (p<0.05) associated with comorbidities, absence of medical intervention, severe disabilities and disabilities acquired at birth. After adjusting for individual-level factors (age, sex, education, employment and physical activities), the level of disability and treatment accessibility were significantly associated with depression. After adjusting for family and community-level factors (economic status, experience of violence and social participation), depression remained significantly associated (p<0.05) with having comorbidities, absence of medical intervention and presence of very severe disabilities. When adjusting for both individual-level and community-level factors, the level of disability continued to show a significant association with depression (OR 6.36 (moderate vs mild), 2.11 (severe vs mild) and 13.3 (very severe vs mild), overall p-value of 0.045). Across all three adjusted models, the level of disability was significantly associated with depression (p<0.05).

CONCLUSION

Depression is one of the major global public health concerns, with people with disabilities being particularly vulnerable. Ensuring the health and well-being of people with disabilities requires focused attention and strategic planning, emphasising disease prevention, health promotion and improved access to care.

摘要

目的

评估残疾人群中抑郁症的患病率及其相关因素。

设计

横断面研究。

背景

2019年10月至11月在尼泊尔伊拉姆市开展的基于社区的研究。

参与者

该研究在164名有身体、听力和视力相关残疾的人群中进行。参与者通过简单随机抽样方法,使用从伊拉姆市获得的抽样框架进行选取。

主要观察指标

残疾人群中的抑郁症及其相关因素。通过经过验证的尼泊尔语版医院焦虑抑郁量表评估抑郁症。数据收集基于预先测试的结构化问卷。

结果

残疾人群中抑郁症的患病率为39%,29.9%的受访者处于边缘性抑郁状态。在未调整分析中,抑郁症与合并症、未接受医疗干预、严重残疾以及出生时获得的残疾显著相关(p<0.05)。在调整个体层面因素(年龄、性别、教育程度、就业和体育活动)后,残疾程度和治疗可及性与抑郁症显著相关。在调整家庭和社区层面因素(经济状况、暴力经历和社会参与)后,抑郁症仍与合并症、未接受医疗干预以及存在非常严重的残疾显著相关(p<0.05)。在同时调整个体层面和社区层面因素时,残疾程度继续与抑郁症显示出显著关联(比值比6.36(中度与轻度相比),2.11(重度与轻度相比)和13.3(非常重度与轻度相比),总体p值为0.045)。在所有三个调整模型中,残疾程度与抑郁症显著相关(p<0.05)。

结论

抑郁症是全球主要的公共卫生问题之一,残疾人群尤其易受影响。确保残疾人群的健康和福祉需要重点关注和战略规划,强调疾病预防、健康促进以及改善医疗服务可及性。

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