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身体和感官残疾成年人中抑郁症的发病率、风险及相关因素:一项基于全国人口的研究。

Incidence, risk, and associated factors of depression in adults with physical and sensory disabilities: A nationwide population-based study.

作者信息

Shen Szu-Ching, Huang Kuang-Hua, Kung Pei-Tseng, Chiu Li-Ting, Tsai Wen-Chen

机构信息

Department of Public Health, China Medical University, Taichung, Taiwan, R.O.C.

Department of Health Services Administration, China Medical University, Taichung, Taiwan, R.O.C.

出版信息

PLoS One. 2017 Mar 31;12(3):e0175141. doi: 10.1371/journal.pone.0175141. eCollection 2017.

Abstract

BACKGROUND

Physical disability has been associated with the risk of depression. We examined the incidence, risk, and associated factors of depression in Taiwanese adults with physical/sensory disabilities.

METHODS

Two national databases were used to retrospectively analyze 749,491 ≥20-year-old Taiwanese with physical/sensory disabilities in 2002-2008. The incidence of depression was analyzed by univariate Poisson regression. Risk factors of depression were followed up through 2014 and examined with a Cox proportional hazards model.

RESULTS

Among the study subjects, the incidence of depression was 6.29 per 1000 person-years, with 1.83 per 1000 person-years corresponding to major depression. The subjects' depression risk was affected by disability type, disability severity, gender, age, education, marital status, aboriginal status, monthly salary, residence urbanization level, and Charlson comorbidity index (CCI). Subjects with rare diseases, mild disability, female gender, age 35-44 years, a high school education level, divorced/widowed status, non-aboriginal status, a NT$22,801-28,800 monthly salary, a highly urbanized residence area, or a CCI≥3 were at higher risk for depression.

CONCLUSIONS AND IMPLICATIONS

Adults with physical/sensory disabilities have a 3.7-fold higher incidence of depression than the general population. Social services departments and family members should take extra measures toward preventing and treating depression in this subpopulation.

摘要

背景

身体残疾与抑郁症风险相关。我们研究了台湾身体/感官残疾成年人中抑郁症的发病率、风险及相关因素。

方法

利用两个全国性数据库对2002年至2008年749,491名年龄≥20岁的台湾身体/感官残疾者进行回顾性分析。采用单变量泊松回归分析抑郁症发病率。对抑郁症的危险因素随访至2014年,并采用Cox比例风险模型进行检验。

结果

在研究对象中,抑郁症发病率为每1000人年6.29例,其中重度抑郁症为每1000人年1.83例。研究对象的抑郁症风险受残疾类型、残疾严重程度、性别、年龄、教育程度、婚姻状况、原住民身份、月工资、居住城市化水平和Charlson合并症指数(CCI)影响。患有罕见病、轻度残疾、女性、年龄35 - 44岁、高中学历、离婚/丧偶、非原住民身份、月工资22,801 - 28,800新台币、居住在高度城市化地区或CCI≥3的研究对象患抑郁症风险更高。

结论与启示

身体/感官残疾成年人患抑郁症的发病率比普通人群高3.7倍。社会服务部门和家庭成员应采取额外措施预防和治疗该亚人群的抑郁症。

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