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下一代药物清除率见解:肝胆和肾脏系统中的实时追踪

Next generation drug clearance insights: real-time tracking in hepatobiliary and renal systems.

作者信息

Hur Won, Seong Gi Hun, Choi Hak Soo

机构信息

Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02124, USA.

Department of Bionano Engineering, Center for Bionano Intelligence Education and Research, Hanyang University, Ansan, 426-791, South Korea.

出版信息

Light Sci Appl. 2025 Feb 26;14(1):98. doi: 10.1038/s41377-025-01782-5.

Abstract

The integration of spatiotemporally resolved clearance pathway tracking (SRCPT) provides a new lens for evaluating drug clearance pathways, enabling precise mapping of physiological conditions of metabolic organs, such as liver or kidney impairment.

摘要

时空分辨清除途径追踪(SRCPT)的整合为评估药物清除途径提供了一个新视角,能够精确绘制代谢器官的生理状况,如肝脏或肾脏损伤情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02a2/11862125/5305390b72f4/41377_2025_1782_Fig1_HTML.jpg

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