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健康心脏工具的实施——一种对重度精神疾病患者具有潜在心脏代谢健康益处的算法。

Implementation of the healthy heart tool- an algorithm with potential cardiometabolic health benefits in persons with severe mental illness.

作者信息

Lund-Stenvold Elisabeth Haug, Ringen Petter A, Andreassen Ole A, Gaarden Torfinn L, Hartberg Cecilie B, Johnsen Erik, Myklatun Silje, Osnes Kåre, Sørensen Kjetil, Vaaler Arne, Tonstad Serena, Engh John A, Høye Anne

机构信息

Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

Division of Mental Health and Substance Abuse, University Hospital of North Norway, Tromsø, Norway.

出版信息

BMC Psychiatry. 2025 Feb 25;25(1):172. doi: 10.1186/s12888-025-06578-w.

Abstract

BACKGROUND

Cardiometabolic diseases are the main causes of death in persons with severe mental illness (SMI), highlighting the need to improve management of cardiovascular risk factors in both primary and specialized health care. The "Healthy Heart Tool" aims at helping health care workers to identify persons at risk, and to initiate proper interventions. Here we investigate if the recommendations in the Healthy Heart Tool are followed one year after implementation and whether implementation of the tool improved cardiometabolic risk factors in SMI.

METHODS

Data from 270 individuals with SMI from six Norwegian hospitals were collected at baseline and at 12 months after implementation of the Healthy Heart Tool throughout the health care services. Changes from baseline to 12 months follow-up were analyzed using chi-square and independent t-tests, whereas implementation effects were analyzed using logistic general linear mixed models.

RESULTS

After implementing the Healthy Heart Tool, significantly more persons received dietary advice and/or salt restriction advice (75.5% vs. 84.8%, p = 0.035). After controlling for Body Mass Index (BMI) ≥ 30 and sex, there was an odds ratio (OR) of 8.9 (95% CI 1.42-55.77) for receiving dietary advice and/or advice on salt reduction. There was a significant reduction (p = 0.016) in numbers of participants with high levels of total serum cholesterol ≥ 5 mmol/ (54.4% vs. 46.3%).

CONCLUSIONS

Implementing the Healthy Heart Tool can increase awareness of cardiovascular risk factors in patients with SMI. The intervention increased the proportion of individuals who received dietary and salt reduction advice and decreased the proportion of individuals with high cholesterol levels. However, due to the small numbers, these results should be interpreted with caution. Nonetheless, the findings suggest that the Healthy Heart Tool may be an effective means for improving the management of cardiovascular risk factors in individuals with SMI in typical clinical settings.

TRIAL REGISTRATIONS

The trial was retrospectively registered in ClinicalTrials.gov 29.01.25, ID NCT06807242.

摘要

背景

心脏代谢疾病是严重精神疾病(SMI)患者的主要死因,这凸显了在初级和专科医疗保健中改善心血管危险因素管理的必要性。“健康心脏工具”旨在帮助医护人员识别有风险的人群,并启动适当的干预措施。在此,我们调查在实施“健康心脏工具”一年后,其建议是否得到遵循,以及该工具的实施是否改善了SMI患者的心脏代谢危险因素。

方法

在整个医疗保健服务机构实施“健康心脏工具”的基线期和实施后12个月,收集了来自挪威六家医院的270名SMI患者的数据。使用卡方检验和独立t检验分析从基线到12个月随访的变化,而使用逻辑广义线性混合模型分析实施效果。

结果

实施“健康心脏工具”后,接受饮食建议和/或限盐建议的人数显著增加(75.5%对84.8%,p = 0.035)。在控制体重指数(BMI)≥30和性别后,接受饮食建议和/或减盐建议的比值比(OR)为8.9(95%可信区间1.42 - 55.77)。血清总胆固醇水平≥5 mmol/的参与者数量显著减少(p = 0.016)(54.4%对46.3%)。

结论

实施“健康心脏工具”可提高SMI患者对心血管危险因素的认识。该干预措施增加了接受饮食和减盐建议的个体比例,并降低了高胆固醇水平个体的比例。然而,由于样本量较小,这些结果应谨慎解释。尽管如此,研究结果表明“健康心脏工具”可能是在典型临床环境中改善SMI个体心血管危险因素管理的有效手段。

试验注册

该试验于2025年1月29日在ClinicalTrials.gov进行回顾性注册,标识符为NCT06807242。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ff/11863842/2eaee79132e1/12888_2025_6578_Fig1_HTML.jpg

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