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[妊娠合并晚期妊娠中毒症母亲的子女。一项前瞻性“妊娠与儿童发育过程”研究计划的结果]

[Children of mothers with late gestosis in pregnancy. Results of a prospective "course of pregnancy and child development" study program].

作者信息

Manzke H, Reinhold G

出版信息

Monatsschr Kinderheilkd. 1985 Apr;133(4):246-9.

PMID:4000141
Abstract

Within the sample of 1783 children from the prospective study "Schwangerschaftsverlauf und Kindesentwicklung" (Course of pregnancy and development of children) followed-up until the age of 6 years the mothers of 182 suffered from late gestosis (10.2%). The values of the systolic blood pressure and of the protein concentration in the urine of the mothers measured at their last examination before onset of labour were crucial for the diagnosis of gestosis. According to this definition 95 mothers with systolic pressure greater than or equal to 150 mm Hg were classified as hypertensive (group of the hypertension children) and 87 mothers with both systolic pressure greater than or equal to 150 mm Hg and proteinuria greater than 1 g/l as being preeclamptic (group of the preeclamptic children). The control groups contained the same number of children (matched pairs). There were no significant differences in the findings between the different groups. Apparently, the prognosis of the child's development is favourable provided that the gestosis does not last long and does not lead to placental insufficiency.

摘要

在“孕期及儿童发育”前瞻性研究的1783名儿童样本中,随访至6岁时,182名儿童的母亲患有晚期妊娠中毒症(10.2%)。分娩前最后一次检查时测量的母亲收缩压值和尿蛋白浓度值对妊娠中毒症的诊断至关重要。根据这一定义,95名收缩压大于或等于150毫米汞柱的母亲被归类为高血压(高血压儿童组),87名收缩压大于或等于150毫米汞柱且蛋白尿大于1克/升的母亲被归类为先兆子痫(先兆子痫儿童组)。对照组包含相同数量的儿童(配对)。不同组之间的研究结果没有显著差异。显然,只要妊娠中毒症持续时间不长且不导致胎盘功能不全,儿童发育的预后是良好的。

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