Suppr超能文献

接受体外受精的女性的血栓形成风险:一项叙述性综述。

Risk of Thrombosis in Women Undergoing In Vitro Fertilization: A Narrative Review.

作者信息

Grandone Elvira, Bitsadze Victoria, Khizroeva Jamilya, Chinni Elena, Mastroianno Mario, Nappi Luigi, Tretyakova Maria, Makatsariya Natalia, Grigoreva Kristina, Gashimova Nilufar, Lazarchuk Arina, Kapanadze Daredzhan, Polyakova Tatyana, Shatilina Anastasia, Lyadnova Elizaveta, Blbulyan Armen, Kuneshko Nart, Zainulina Marina, Gerotziafas Grigoris, Makatsariya Alexander

机构信息

Department of Obstetrics, Gynecology and Perinatal Medicine, The I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya Str. 8-2, 119435 Moscow, Russia.

Thrombosis and Hemostasis Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.

出版信息

J Clin Med. 2025 Feb 7;14(4):1053. doi: 10.3390/jcm14041053.

Abstract

This narrative review summarizes the available literature on the association between In Vitro Fertilization (IVF) treatments and thrombosis, focusing on epidemiology and pathophysiology. Thrombosis is a rare IVF-related complication, with an incidence of approximately 0.2%, dramatically increased by ovarian hyperstimulation syndrome (OHSS). Arterial thrombosis, primarily associated with OHSS, is a rare and early event, while venous thrombosis, although more common, remains a rare complication of IVF. Venous thrombosis often affects the upper body. The thrombotic risk is higher during the first trimester of pregnancy obtained through IVF. This review discusses the impact of risk factors such as OHSS, thrombophilia, obesity, advanced maternal age, and polycystic ovarian syndrome, which predispose women to thromboembolic events during and after IVF stimulation.

摘要

本叙述性综述总结了关于体外受精(IVF)治疗与血栓形成之间关联的现有文献,重点关注流行病学和病理生理学。血栓形成是一种罕见的与IVF相关的并发症,发病率约为0.2%,卵巢过度刺激综合征(OHSS)会使其显著增加。动脉血栓形成主要与OHSS相关,是一种罕见且发生较早的事件,而静脉血栓形成虽然更为常见,但仍是IVF的一种罕见并发症。静脉血栓形成常累及上半身。通过IVF受孕的妊娠头三个月血栓形成风险更高。本综述讨论了OHSS、血栓形成倾向、肥胖、高龄产妇和多囊卵巢综合征等风险因素的影响,这些因素使女性在IVF刺激期间及之后易发生血栓栓塞事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2ec/11856335/a1e320d75f86/jcm-14-01053-g001.jpg

相似文献

1
Risk of Thrombosis in Women Undergoing In Vitro Fertilization: A Narrative Review.
J Clin Med. 2025 Feb 7;14(4):1053. doi: 10.3390/jcm14041053.
3
Thrombosis following ovarian hyperstimulation syndrome.
Gynecol Endocrinol. 2014 Nov;30(11):764-8. doi: 10.3109/09513590.2014.927858. Epub 2014 Jul 11.
5
Increased venous thrombosis incidence in pregnancies after in vitro fertilization.
Hum Reprod. 2014 Mar;29(3):611-7. doi: 10.1093/humrep/det458. Epub 2014 Jan 6.
6
Risk of thrombosis in women with malignancies undergoing ovarian stimulation for fertility preservation.
Hum Reprod Update. 2014 Nov-Dec;20(6):944-51. doi: 10.1093/humupd/dmu035. Epub 2014 Jul 10.
7
Volume expanders for the prevention of ovarian hyperstimulation syndrome.
Cochrane Database Syst Rev. 2016 Aug 31;2016(8):CD001302. doi: 10.1002/14651858.CD001302.pub3.
8
Factors Associated with Ovarian Hyperstimulation Syndrome (OHSS) Severity in Women With Polycystic Ovary Syndrome Undergoing IVF/ICSI.
Front Endocrinol (Lausanne). 2021 Jan 19;11:615957. doi: 10.3389/fendo.2020.615957. eCollection 2020.
9
The number of oocytes retrieved during IVF: a balance between efficacy and safety.
Hum Reprod. 2018 Jan 1;33(1):58-64. doi: 10.1093/humrep/dex334.

引用本文的文献

1
Fertility treatments and stroke: a scoping review.
BMJ Open. 2025 Jul 7;15(7):e095199. doi: 10.1136/bmjopen-2024-095199.

本文引用的文献

2
Prevention of moderate and severe ovarian hyperstimulation syndrome: a guideline.
Fertil Steril. 2024 Feb;121(2):230-245. doi: 10.1016/j.fertnstert.2023.11.013. Epub 2023 Dec 13.
3
ART in Europe, 2019: results generated from European registries by ESHRE†.
Hum Reprod. 2023 Dec 4;38(12):2321-2338. doi: 10.1093/humrep/dead197.
5
Venous Thromboembolism Associated with Assisted Reproductive Technology: A Systematic Review and Meta-analysis.
Thromb Haemost. 2023 Mar;123(3):283-294. doi: 10.1055/s-0042-1760255. Epub 2022 Dec 31.
6
The Legacy of Edwards and Steptoe and the Windy Roads of Assisted Reproduction: Where Do We Stand with Venous Thromboembolism?
Thromb Haemost. 2023 Mar;123(3):267-269. doi: 10.1055/a-1996-1341. Epub 2022 Dec 10.
7
Thrombophilia, Inflammation, and Recurrent Pregnancy Loss: A Case-Based Review.
Semin Reprod Med. 2021 Mar;39(1-02):62-68. doi: 10.1055/s-0041-1731827. Epub 2021 Jul 2.
10
Arterial and venous complications after fertility treatment: A French nationwide cohort study.
Eur J Obstet Gynecol Reprod Biol. 2019 Jun;237:57-63. doi: 10.1016/j.ejogrb.2019.02.034. Epub 2019 Mar 11.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验