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Microencapsulation of Probiotics for Enhanced Stability and Health Benefits in Dairy Functional Foods: A Focus on Pasta Filata Cheese.

作者信息

D'Amico Vita, Cavaliere Mariasimona, Ivone Marianna, Lacassia Chiara, Celano Giuseppe, Vacca Mirco, la Forgia Flavia Maria, Fontana Sergio, De Angelis Maria, Denora Nunzio, Lopedota Angela Assunta

机构信息

Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 4, E. Orabona Street, 70125 Bari, Italy.

Department of Soil, Plant and Food Sciences, University of Bari Aldo Moro, 165/A, G. Amendola Street, 70126 Bari, Italy.

出版信息

Pharmaceutics. 2025 Feb 2;17(2):185. doi: 10.3390/pharmaceutics17020185.


DOI:10.3390/pharmaceutics17020185
PMID:40006552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11859715/
Abstract

Probiotics provide significant health benefits, but their viability is often compromised during production, storage, and passage through the gastrointestinal tract. These challenges hinder their effective incorporation into functional applications, particularly in dairy functional foods, in which factors such as acidity, oxygen exposure, and storage conditions negatively impact cell survival. The focus was on functional dairy foods, particularly on pasta filata cheeses. Indeed, the use of probiotics in pasta filata cheeses presents significant challenges due to the specific manufacturing processes, which encompass the application of high temperatures and other harsh conditions. These factors can adversely affect the viability and availability of probiotic microorganisms. However, microencapsulation has emerged as a promising solution, offering a protective barrier that enhances probiotic stability, improves survival rates, and facilitates targeted release in the gastrointestinal environment. This review examines the pivotal role of microencapsulation in stabilising probiotics for functional applications, emphasising its relevance in high-value food systems. Functional applications, including foods designed to offer essential nutritional benefits and promote host health, play a crucial role in disease prevention and immune system support, reducing the risk of infections and other physiological impairments. Key microencapsulation technologies are analysed, focusing on their benefits, limitations, and challenges related to scalability and industrial implementation. Additionally, this review discusses strategies to optimise formulations, ensure the sensory quality of final products, and explore future opportunities for expanding innovative applications that align with growing consumer demand for health-promoting solutions.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/9904c9596906/pharmaceutics-17-00185-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/a5b7bc7f7ac7/pharmaceutics-17-00185-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/e28481c2444d/pharmaceutics-17-00185-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/f8c3ef864767/pharmaceutics-17-00185-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/cd409a1f3b5b/pharmaceutics-17-00185-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/bc910956aade/pharmaceutics-17-00185-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/9904c9596906/pharmaceutics-17-00185-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/a5b7bc7f7ac7/pharmaceutics-17-00185-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/e28481c2444d/pharmaceutics-17-00185-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/f8c3ef864767/pharmaceutics-17-00185-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/cd409a1f3b5b/pharmaceutics-17-00185-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/bc910956aade/pharmaceutics-17-00185-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c498/11859715/9904c9596906/pharmaceutics-17-00185-g006.jpg

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[1]
Microencapsulation of Probiotics for Enhanced Stability and Health Benefits in Dairy Functional Foods: A Focus on Pasta Filata Cheese.

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引用本文的文献

[1]
Genesis, Health Benefits, and Future Perspectives of Probiotics: Exploring Endogenous and Exogenous Classes, Innovations, and Research Gaps.

Probiotics Antimicrob Proteins. 2025-9-10

[2]
Probiotics in Nanotechnology-Driven Wound Healing: From Mechanistic Insight to Clinical Promise.

Pharmaceutics. 2025-6-21

[3]
The Role of Functional Feed in Modulating Fish Gut Microbiome to Enhance Resistance Against Aquaculture Pathogens.

Probiotics Antimicrob Proteins. 2025-7-22

本文引用的文献

[1]
Screening for probiotic properties and potential immunogenic effects of lactobacilli strains isolated from various food products.

Front Microbiol. 2024-10-29

[2]
A Multi-Omics Approach to Disclose Metabolic Pathways Impacting Intestinal Permeability in Obese Patients Undergoing Very Low Calorie Ketogenic Diet.

Nutrients. 2024-6-28

[3]
Is There Evidence to Support Probiotic Use for Healthy People?

Adv Nutr. 2024-8

[4]
Microfluidic Strategies for Encapsulation, Protection, and Controlled Delivery of Probiotics.

J Agric Food Chem. 2024-7-10

[5]
Spray-Dried Nanolipid Powders for Pulmonary Drug Delivery: A Comprehensive Mini Review.

Pharmaceutics. 2024-5-17

[6]
Multistimuli responsive microcapsules produced by the prilling/vibration technique for targeted colonic delivery of probiotics.

Int J Pharm. 2024-6-10

[7]
Dynamic microbial and metabolic changes during Apulian Caciocavallo cheesemaking and ripening produced according to a standardized protocol.

J Dairy Sci. 2024-9

[8]
Innovative Pharmaceutical Techniques for Paediatric Dosage Forms: A Systematic Review on 3D Printing, Prilling/Vibration and Microfluidic Platform.

J Pharm Sci. 2024-7

[9]
Microfluidic-based multifunctional microspheres for enhanced oral co-delivery of probiotics and postbiotics.

Biomaterials. 2024-7

[10]
Investigating the prilling/vibration technique to produce gastric-directed drug delivery systems for misoprostol.

Int J Pharm. 2024-2-15

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