Junginger H E
Pharm Weekbl Sci. 1985 Apr 26;7(2):59-62. doi: 10.1007/BF02106128.
Within the Center for Bio-Pharmaceutical Sciences the release characteristics of drugs form the major research object of the Division of Pharmaceutical Technology. Transdermal systems are being developed that can supply a drug during several days. Irritation of the skin may be avoided by using hydrogels. To enable long-term transdermal application also the colloidal structure of creams and ointments is investigated. As most drugs are to be taken orally, however, a research project was also started to make cheap and easy to produce controlled release tablets. The results with a microporous polypropylene polymer are promising.
在生物制药科学中心内,药物的释放特性是药物技术部门的主要研究对象。正在研发能在数天内持续给药的透皮系统。使用水凝胶可避免皮肤刺激。为实现长期透皮给药,还对乳膏和软膏的胶体结构进行了研究。然而,由于大多数药物需口服,因此还启动了一个研究项目,旨在生产廉价且易于制造的控释片剂。一种微孔聚丙烯聚合物的研究结果很有前景。