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病例报告:右主支气管小叶状毛细血管瘤:伴有钙化及囊性淋巴结的罕见病例。

Case report: Lobular capillary hemangioma of the right main bronchus: a rare case with calcified and cystic lymph nodes.

作者信息

Chen Xu-Ping, Zeng Jia, Zhang Wei, Wu Peng, Zhao Yan-Ling, Li Zhi-Shu, Shen Ling, He Shi-Xu

机构信息

Department of Respiratory and Critical Care Medicine, Guangyuan Central Hospital, Guangyuan, Sichuan, China.

Department of Respiratory and Critical Care Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Zhejiang, China.

出版信息

Front Med (Lausanne). 2025 Feb 12;12:1501312. doi: 10.3389/fmed.2025.1501312. eCollection 2025.

DOI:10.3389/fmed.2025.1501312
PMID:40012982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11862995/
Abstract

Lobular capillary hemangioma (LCH), typically a benign vasoproliferative lesion of the skin or mucosal surfaces, is exceptionally rare in the trachea. Now, we present the second reported case of LCH found in the right intermediate bronchus, characterized by calcification within the lesion and cystic changes. These distinctive features should alert clinicians to consider LCH in the differential diagnosis of other benign vascular tumors and mediastinal lymphadenopathy, particularly when calcified and cystic lesions are observed.

摘要

小叶性毛细血管瘤(LCH)通常是皮肤或黏膜表面的一种良性血管增生性病变,在气管中极为罕见。现在,我们报告第二例在右中间支气管发现的LCH病例,其特征为病变内有钙化及囊性改变。这些独特特征应提醒临床医生在鉴别诊断其他良性血管肿瘤和纵隔淋巴结病时考虑LCH,尤其是当观察到钙化和囊性病变时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/08f3e16a8fea/fmed-12-1501312-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/a02c82008b06/fmed-12-1501312-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/140aaf3d017a/fmed-12-1501312-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/08f3e16a8fea/fmed-12-1501312-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/a02c82008b06/fmed-12-1501312-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/140aaf3d017a/fmed-12-1501312-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7b9/11862995/08f3e16a8fea/fmed-12-1501312-g003.jpg

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本文引用的文献

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Successful management of tracheal lobular capillary hemangioma with arterial embolization followed by electrosurgical snaring flexible bronchoscopy in an 11-year-old boy: A case report and literature review.一名11岁男孩经动脉栓塞治疗气管小叶毛细血管瘤成功,随后通过电子圈套器在柔性支气管镜下进行切除:病例报告及文献综述
Front Med (Lausanne). 2023 Mar 20;10:1088815. doi: 10.3389/fmed.2023.1088815. eCollection 2023.
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Recurrent Alterations in the MAPK pathway in Sporadic Pyogenic Granuloma of Childhood.儿童散发性化脓性肉芽肿中 MAPK 通路的反复改变。
Acta Derm Venereol. 2022 May 19;102:adv00715. doi: 10.2340/actadv.v102.1119.
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ISSVA Classification of Vascular Anomalies and Molecular Biology.
ISSVA 血管异常分类与分子生物学。
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Oral pyogenic granulomas show MAPK/ERK signaling pathway activation, which occurs independently of BRAF, KRAS, HRAS, NRAS, GNA11, and GNA14 mutations.口腔化脓性肉芽肿显示 MAPK/ERK 信号通路激活,这种激活与 BRAF、KRAS、HRAS、NRAS、GNA11 和 GNA14 突变无关。
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Lobular capillary hemangioma of the tracheobronchial tree: A case report and literature review.气管支气管树的小叶状毛细血管瘤:一例报告及文献复习
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