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一种特殊类型巨大胎儿肝脏血管瘤的超声诊断及随访

Ultrasonographic diagnosis and follow-up of a special type of giant fetal hepatic hemangioma.

作者信息

Weng Xiaoyan, Jiang Juan, Wen Gang

机构信息

Ultrasound Department of Women and Children's Hospital Affiliated to Ningbo University, No. 339 Liuting Street, Haishu District, Ningbo, Zhejiang Province, 315000, China.

Neonatal Monitoring Center of Women and Children's Hospital Affiliated to Ningbo University, No. 339 Liuting Street, Haishu District, Ningbo, Zhejiang Province, 315000, China.

出版信息

Pediatr Radiol. 2025 May;55(5):1024-1028. doi: 10.1007/s00247-025-06196-4. Epub 2025 Feb 27.

DOI:10.1007/s00247-025-06196-4
PMID:40014099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12065717/
Abstract

We present a case of giant fetal hepatic hemangioma to illustrate the impact of ultrasound monitoring on treatment outcomes. Prenatal ultrasound revealed cardiac enlargement, leading to a cesarean section. The neonate had multiple vascular anomalies, including hepatic artery-portal fistula, portal-hepatic venous fistula, and a giant arteriovenous fistula for the abnormal right internal thoracic artery with portal vein, causing progressive pulmonary hypertension. Postnatal embolization and propranolol treatment resulted in significant tumor shrinkage on ultrasonography and resolution by age 2 years. This report highlights the value of detailed prenatal ultrasound monitoring in guiding effective treatment and improving outcomes for giant fetal hepatic hemangioma, a rare but potentially life-threatening condition.

摘要

我们报告一例巨大胎儿肝血管瘤病例,以说明超声监测对治疗结果的影响。产前超声显示心脏扩大,遂行剖宫产。新生儿有多种血管异常,包括肝动脉-门静脉瘘、门静脉-肝静脉瘘,以及异常的右胸廓内动脉与门静脉形成的巨大动静脉瘘,导致进行性肺动脉高压。产后栓塞和普萘洛尔治疗使超声检查显示肿瘤显著缩小,并在2岁时消退。本报告强调了详细的产前超声监测在指导有效治疗和改善巨大胎儿肝血管瘤(一种罕见但可能危及生命的疾病)治疗结果方面的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a443/12065717/5f6e0d2b7ebd/247_2025_6196_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a443/12065717/1c7c9757b140/247_2025_6196_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a443/12065717/5f6e0d2b7ebd/247_2025_6196_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a443/12065717/1c7c9757b140/247_2025_6196_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a443/12065717/5f6e0d2b7ebd/247_2025_6196_Fig2_HTML.jpg

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本文引用的文献

1
Imaging of solid congenital abdominal masses: a review of the literature and practical approach to image interpretation.先天性腹腔实性肿块的影像学诊断:文献复习及实用影像学解读方法。
Pediatr Radiol. 2020 Dec;50(13):1907-1920. doi: 10.1007/s00247-020-04678-1. Epub 2020 Nov 30.
2
[Prenatal diagnosis and management of fetal hepatic hemangioma].[胎儿肝脏血管瘤的产前诊断与处理]
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2019 Jun 25;48(4):439-445. doi: 10.3785/j.issn.1008-9292.2019.08.15.
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Infantile hepatic hemangioma: current state of the art, controversies, and perspectives.婴儿型肝血管瘤:现状、争议与展望。
Eur J Pediatr. 2020 Jan;179(1):1-8. doi: 10.1007/s00431-019-03504-7. Epub 2019 Nov 22.
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Prenatal diagnosis of a liver cavernous hemangioma.肝脏海绵状血管瘤的产前诊断
Fetal Pediatr Pathol. 2013 Oct;32(5):341-5. doi: 10.3109/15513815.2013.768737. Epub 2013 Feb 19.
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Giant fetal hepatic hemangioma. Case report and literature review.巨大胎儿肝脏血管瘤。病例报告及文献综述。
Fetal Diagn Ther. 2003 Jan-Feb;18(1):59-64. doi: 10.1159/000066387.