Rodda Luke N, Candela Kylie E, Hart Amy P, Moffatt Ellen G, Pearring Sue, Scott Karen S
Office of the Chief Medical Examiner, San Francisco, CA.
Department of Laboratory Medicine, University of California, San Francisco, CA.
Am J Forensic Med Pathol. 2025 Sep 1;46(3):217-221. doi: 10.1097/PAF.0000000000001034. Epub 2025 Jul 24.
In postmortem forensic investigations, where the bladder is voided or dehydrated prior to autopsy, it is possible to wash the bladder with saline to collect the resulting "bladder wash" and any residual urine for toxicological analysis. Although this method is not yet commonplace or standard, a recent study has demonstrated that bladder wash is an effective alternative specimen in postmortem forensic toxicology. The current study aimed to assess forensic pathologists' opinions on the use of bladder wash samples both before and after reviewing bladder wash toxicological data. An online survey was distributed to forensic pathologists from NAME, and responses were analyzed to identify any shifts in perceptions after data presentation. The findings revealed that most forensic pathologists recognized the benefits of bladder wash collection and analysis as well as its usefulness in determining the cause and manner of death, with noticeable changes in perspective following exposure to supporting data. This study highlights the potential value of standardizing the easy and accessible collection of bladder wash for postmortem toxicological analysis, thereby providing forensic pathologists with invaluable information when other biological specimens are unavailable.
在尸体解剖法医调查中，若在尸检前膀胱已排空或脱水，可用生理盐水冲洗膀胱，收集产生的“膀胱冲洗液”及任何残留尿液进行毒理学分析。尽管这种方法尚未普遍或成为标准方法，但最近一项研究表明，膀胱冲洗液是尸体解剖法医毒理学中一种有效的替代样本。本研究旨在评估法医病理学家在审查膀胱冲洗液毒理学数据前后对使用膀胱冲洗液样本的看法。向来自[机构名称]的法医病理学家进行了在线调查，并对回复进行分析，以确定在展示数据后看法是否有任何转变。研究结果显示，大多数法医病理学家认识到收集和分析膀胱冲洗液的益处及其在确定死因和死亡方式方面的有用性，在接触支持性数据后观点有明显变化。本研究强调了标准化简单且可获取的膀胱冲洗液收集方法用于尸体解剖毒理学分析的潜在价值，从而在其他生物样本无法获取时为法医病理学家提供宝贵信息。
