Augsburger J J, Gamel J W, Bailey R S, Donoso L A, Gonder J R, Shields J A
Retina. 1985 Winter-Spring;5(1):26-9.
The authors reviewed the clinical records of 50 patients who underwent enucleation for posterior uveal malignant melanoma to determine the correlation between clinical estimates of tumor size made prior to enucleation and pathologic measurements made during gross examination. Linear regression of the pathologic measurements of several tumor dimensions on the corresponding clinical estimates documented correlation coefficients ranging from 0.81 for minimal basal diameter to 0.92 for tumor thickness. Although these values suggest a high level of linear correlation, wide confidence limits indicate a significant level of random variation in the data points. Further, nonzero intercepts and nonunity slopes of the linear regression lines indicate a systematic variation between clinical estimates and gross pathologic measurements of tumor size.
作者回顾了50例因后葡萄膜恶性黑色素瘤而接受眼球摘除术患者的临床记录，以确定眼球摘除术前对肿瘤大小的临床估计与大体检查时的病理测量之间的相关性。对几个肿瘤维度的病理测量值与相应临床估计值进行线性回归分析，结果显示相关系数范围从最小基底直径的0.81到肿瘤厚度的0.92。尽管这些值表明线性相关性较高，但较宽的置信区间表明数据点存在显著程度的随机变异。此外，线性回归线的非零截距和非单位斜率表明肿瘤大小的临床估计值与大体病理测量值之间存在系统性变异。
