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猫背根神经节中神经元胞体的板层状排列。

Lamellar arrangement of neuronal somata in the dorsal root ganglion of the cat.

作者信息

Kausz M, Réthelyi M

出版信息

Somatosens Res. 1985;2(3):193-204. doi: 10.3109/07367228509144563.

DOI:10.3109/07367228509144563
PMID:4001674
Abstract

The retrograde transport of horseradish peroxidase (HRP) was used to study the distribution of perikarya in the dorsal root ganglia (DRGs). Injections of HRP subcutaneously into a small area of the foreleg, flank, perineum, the central pad of the forepaw, muscles of the foreleg, the wall of the urinary bladder, and mucosa of the rectum resulted in many retrogradely labeled perikarya in one DRG. Labeled perikarya were distributed in the ganglia proximally to distal elongated slabs or columns, especially in cases of subcutaneous injections. A similar slab, or columnar distribution, of HRP-labeled perikarya was noticed when the tracer was injected into the spinal cord preceded by the transection of all dorsal root filaments but one. Perikarya located along the lateral border of the ganglion were labeled through rostral filaments, and perikarya distributed along the medial border were labeled through caudal filaments. A segmental somatotopic map has been conceived for the DRG as an intermediate territory between the periphery and the spinal cord.

摘要

利用辣根过氧化物酶(HRP)的逆行运输来研究背根神经节(DRG)中神经元胞体的分布。将HRP皮下注射到前肢、胁腹、会阴、前爪中央肉垫、前肢肌肉、膀胱壁和直肠黏膜的小区域,导致一个DRG中有许多逆行标记的神经元胞体。标记的神经元胞体分布在神经节近端至远端的细长板或柱状区域,皮下注射的情况尤其如此。当在切断除一根以外的所有背根细丝后将示踪剂注入脊髓时,也观察到了HRP标记的神经元胞体类似的板状或柱状分布。沿神经节外侧缘分布的神经元胞体通过向头侧的细丝被标记,而沿内侧缘分布的神经元胞体通过向尾侧的细丝被标记。已经设想出DRG的节段性躯体定位图,将其作为外周和脊髓之间的中间区域。

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