Malinowska A
Pol Arch Weter. 1979;22(1):87-99.
The purpose of the studies was to determine the activity of enzymes in the serum and pig organs with colibacteriosis in the form of oedema and stomach-intestines disease playing a diagnostic role in the determination of the organ damage degree. Studies were carried out on 29 pigs. The activity of LAP, GPT, GOT, AM, FDPA, Lp, AP and AcP was determined in the serum liver, empty intestines and kidneys of the diseased and control pigs. It resulted from the experiments that in the serum of all the diseased animals the activity of FDPA and GOT was considerably increased and that of AP decreased. So, activity determination does not allow to differentiate both forms of colibacteriosis. AM activity increases only in the serum of oedema pigs. In colibacteriosis of pigs the determination of FDPA activity is the most sensitive enzymatic test. In both diseases the activity of this enzyme increases considerable in the serum and all the studied organs. The activity of the studied enzymes shows that in both forms of collibacteriosis of pigs liver, intestines and kidneys are damaged.
这些研究的目的是确定患有水肿型和胃肠疾病型大肠杆菌病的猪血清及器官中酶的活性，这些酶活性在判定器官损伤程度方面具有诊断作用。对29头猪进行了研究。测定了患病猪和对照猪血清、肝脏、空肠及肾脏中LAP、GPT、GOT、AM、FDPA、Lp、AP和AcP的活性。实验结果显示，所有患病动物血清中FDPA和GOT的活性显著升高，AP的活性降低。因此，通过活性测定无法区分这两种大肠杆菌病类型。AM活性仅在水肿型猪的血清中升高。在猪大肠杆菌病中，FDPA活性测定是最敏感的酶学检测方法。在这两种疾病中，该酶在血清及所有研究器官中的活性均显著升高。所研究酶的活性表明，在猪的两种大肠杆菌病类型中，肝脏、肠道和肾脏均受到损伤。
