对抗心力衰竭机制是使患者消肿同时改善预后的最有效方法。
Counteracting the Mechanisms of Heart Failure is the Most Effective Way to Decongest Patients while Improving Outcomes.
作者信息
Čelutkienė Jelena, Mebazaa Alexandre, Biegus Jan, Ponikowski Piotr, Davison Beth, Cotter Gad
机构信息
Clinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University Vilnius, Lithuania.
INSERM UMR-S 942 (MASCOT), Université Paris Cité Paris, France.
出版信息
Card Fail Rev. 2025 Feb 4;11:e02. doi: 10.15420/cfr.2024.19. eCollection 2025.
Diuretic therapy is not associated with improved outcomes in heart failure and may cause significant side effects. Counteracting the core pathophysiological mechanisms of heart failure through neurohormonal blockade while reducing reliance on diuretics is potentially the most effective method of decongestion.
利尿剂治疗与心力衰竭患者预后改善无关，且可能会引起严重的副作用。通过神经激素阻断来对抗心力衰竭的核心病理生理机制，同时减少对利尿剂的依赖，可能是最有效的消肿方法。
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