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对一个已识别神经元的细胞内刺激会引发心加速肽的释放。

Intracellular stimulation of an identified neuron evokes cardioacceleratory peptide release.

作者信息

Tublitz N J, Truman J W

出版信息

Science. 1985 May 24;228(4702):1013-5. doi: 10.1126/science.4001929.

DOI:10.1126/science.4001929
PMID:4001929
Abstract

The central nervous system of the tobacco hawkmoth, Manduca sexta, is known to contain two cardioacceleratory peptides (CAP's), both of which function in vivo as cardioregulatory neurohormones. Intracellular electrical stimulation of a single abdominal ganglion neuron evokes the release of CAP-like bioactivity. This stimulation-evoked bioactivity is destroyed by prior treatment with protease. The possibility that intracellular stimulation of a CAP-containing neuron synaptically activated additional spiking neurons is eliminated.

摘要

烟草天蛾(烟草天蛾)的中枢神经系统已知含有两种心加速肽(CAP's),这两种肽在体内均作为心脏调节神经激素发挥作用。对单个腹神经节神经元进行细胞内电刺激会引发CAP样生物活性的释放。这种刺激引发的生物活性会被蛋白酶预处理破坏。含有CAP的神经元通过突触激活其他放电神经元的细胞内刺激的可能性被排除。

相似文献

1
Intracellular stimulation of an identified neuron evokes cardioacceleratory peptide release.对一个已识别神经元的细胞内刺激会引发心加速肽的释放。
Science. 1985 May 24;228(4702):1013-5. doi: 10.1126/science.4001929.
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Identification of neurones containing cardioacceleratory peptides (CAPs) in the ventral nerve cord of the tobacco hawkmoth, Manduca sexta.
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J Exp Biol. 1985 Jan;114:381-95. doi: 10.1242/jeb.114.1.381.
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Immunological, biochemical and physiological analyses of cardioacceleratory peptide 2 (CAP2) activity in the embryo of the tobacco hawkmoth Manduca sexta.
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Insect cardioactive peptides. I. Distribution and molecular characteristics of two cardioacceleratory peptides in the tobacco hawkmoth, Manduca sexta.昆虫心脏活性肽。I. 烟草天蛾曼陀罗六斑蛾中两种心脏加速肽的分布和分子特征。
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