Suppr超能文献

全内镜下腰椎间盘切除术:我们终于做到了吗?对其与非显微镜下椎间盘切除术、显微椎间盘切除术和管状椎间盘切除术疗效对比的荟萃分析

Full-endoscopic lumbar spine discectomy: Are We Finally There? A Meta-Analysis of Its Effectiveness Against Non-microscopic Discectomy, Microdiscectomy and Tubular Discectomy.

作者信息

Latka Kajetan, Kozlowska Klaudia, Domisiewicz Kacper, Klepinowski Tomasz, Latka Dariusz

机构信息

Department of Neurology, St Hedwig's Regional Specialist Hospital, Institute of Medical Sciences, University of Opole, Wodociagowa 4, Opole, 45-221 Poland.

Department of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, Wroclaw, 50-370 Poland.

出版信息

Spine J. 2025 Feb 28. doi: 10.1016/j.spinee.2025.02.006.

Abstract

BACKGROUND CONTEXT

Full-endoscopic lumbar discectomy (FELD) has gained increasing attention as a minimally invasive alternative to conventional microdiscectomy (MD), tubular discectomy (MED), and open non-microscopic discectomy (OD) Despite significant technological advancements in endoscopic techniques over the past decade, it is not yet clear whether FELD offers a definitive advantage over traditional methods.

PURPOSE

This study aims to perform a meta-analysis of available publications to assess whether the superiority of endoscopic treatment over traditional open and minimally invasive endoscopic surgical techniques can be more conclusively established. The central question driving this meta-analysis was: Are we finally there?

STUDY DESIGN/SETTING: Meta-analysis study included adult patients (≥18 years old) with symptomatic lumbar disc herniation (LDH) without concurrent lumbar spinal stenosis METHODS: A systematic review was conducted in PubMed, Embase, Web of Science, and the Cochrane Library for randomized or nonrandomized controlled trials published between 2013 and 2024. The quality of randomized controlled trials and cohort studies was assessed using the Revised Cochrane risk-of-bias tool and Newcastle-Ottawa Scale, respectively. Included studies reported on at least one of the following outcomes: (1) adverse effects, (2) operative parameters, (3) bed and hospital stay, and (4) clinical indices (postoperative values). Mean differences (MDs) or odds ratios (ORs) were used to compare treatment effects between FELD and MD, MED, or OD.

RESULTS

FELD demonstrated several advantages, particularly in short-term pain (within 6 months postoperatively) relief and faster patient (length of bed stay 1-2 days) mobilization, while maintaining comparable risks of recurrence, reoperation, and complications relative to traditional techniques. However, there is substantial heterogeneity in the data and a limited number of prospective trials.

CONCLUSIONS

More well-designed, prospective randomized trials are necessary, with a focus on radiological outcomes and comprehensive cost analyses including societal costs. Only through such robust data can we determine whether FELD truly represents a new gold standard for lumbar discectomy. Are we finally there? We are certainly closer, but much remains to be addressed.

摘要

背景

全内镜下腰椎间盘切除术(FELD)作为传统显微椎间盘切除术(MD)、管状椎间盘切除术(MED)和开放非显微椎间盘切除术(OD)的微创替代方法,越来越受到关注。尽管在过去十年中内镜技术取得了重大技术进步,但FELD是否比传统方法具有决定性优势尚不清楚。

目的

本研究旨在对现有出版物进行荟萃分析,以评估内镜治疗相对于传统开放和微创内镜手术技术的优越性是否能得到更确凿的证实。推动这项荟萃分析的核心问题是:我们终于做到了吗?

研究设计/设置:荟萃分析研究纳入了有症状的腰椎间盘突出症(LDH)且无并发腰椎管狭窄的成年患者(≥18岁)。方法:在PubMed、Embase、科学网和Cochrane图书馆中对2013年至2024年发表的随机或非随机对照试验进行系统评价。分别使用修订的Cochrane偏倚风险工具和纽卡斯尔-渥太华量表评估随机对照试验和队列研究的质量。纳入研究至少报告了以下结果之一:(1)不良反应,(2)手术参数,(3)卧床和住院时间,以及(4)临床指标(术后值)。使用平均差(MDs)或比值比(ORs)比较FELD与MD、MED或OD之间的治疗效果。

结果

FELD显示出几个优势,特别是在术后6个月内的短期疼痛缓解和患者更快的活动能力(卧床时间为1-2天),同时与传统技术相比,复发、再次手术和并发症的风险相当。然而,数据存在很大异质性,前瞻性试验数量有限。

结论

需要更多设计良好的前瞻性随机试验,重点关注放射学结果和包括社会成本在内的综合成本分析。只有通过如此可靠的数据,我们才能确定FELD是否真的代表了腰椎间盘切除术的新金标准。我们终于做到了吗?我们当然更接近了,但仍有许多问题有待解决。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验