Chin Ein Wan, Goh Liang Chye, Lau May Nak, Abu Bakar Mohd Zulkiflee
Department of Otorhinolaryngology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
University of Malaya, 50603 Kuala Lumpur Wilayah Persekutuan Kuala Lumpur, Kuala Lumpur, Malaysia.
Sleep Breath. 2025 Mar 1;29(1):118. doi: 10.1007/s11325-025-03278-3.
The main purpose of this study is to evaluate the facial morphology of obstructive sleep apnoea (OSA) individuals by using a handheld blue light three-dimensional (3D) scanner (HBL-3DS) in comparison to conventional lateral cephalometric radiography (LCR). Moreover, our research question is to explores the correlation between 3D facial and neck measurements with OSA indices, encompassing the hypoxic burden.
This prospective cross-sectional study included forty-four adults with OSA. We compared three measurements between LCR and HBL-3DS images: modified facial profile angle (MFPA), nasolabial angle (NLA), and mandibular length (ML). Additionally, the 3D images of thirty-four participants with OSA indices were analysed for seventeen parameters, such as angles, ratios, and linear distances.
This study revealed significant strong correlations (p < 0.001) between LCR and HBL-3DS in the measurements of MFPA (r = 0.675), NLA (r = 0.723), and ML (r = 0.675). However, no significant correlation was found between all predictors and the Apnoea-Hypopnea Index (AHI) or Oxygen Desaturation Index (ODI) in the 3D images of the thirty-four participants. Multivariate regression analysis demonstrated an independent negative correlation between mandibular width (MW) and nadir oxygen levels, while an independent positive correlation was observed between inner canthal width and the Rapid-Eye-Movement percentage (REM).
The study highlighted a significant association between LCR and HBL-3DS. HBL-3DS delivers precise 3D facial and neck measurements, presenting itself as a potentially cost-effective, radiation-free, and portable screening method for participants with OSA in clinical settings.
本研究的主要目的是使用手持式蓝光三维(3D)扫描仪(HBL - 3DS)与传统的头颅侧位X线摄影(LCR)相比,评估阻塞性睡眠呼吸暂停(OSA)患者的面部形态。此外,我们的研究问题是探讨3D面部和颈部测量与OSA指标之间的相关性,包括缺氧负担。
这项前瞻性横断面研究纳入了44名患有OSA的成年人。我们比较了LCR和HBL - 3DS图像之间的三项测量值:改良面部轮廓角(MFPA)、鼻唇角(NLA)和下颌长度(ML)。此外,对34名具有OSA指标的参与者的3D图像进行了17项参数分析,如角度、比例和线性距离。
本研究显示,在MFPA(r = 0.675)、NLA(r = 0.723)和ML(r = 0.675)测量中,LCR与HBL - 3DS之间存在显著的强相关性(p < 0.001)。然而,在34名参与者的3D图像中,所有预测指标与呼吸暂停低通气指数(AHI)或氧饱和度下降指数(ODI)之间均未发现显著相关性。多变量回归分析表明,下颌宽度(MW)与最低氧水平之间存在独立的负相关,而内眦间距与快速眼动百分比(REM)之间存在独立的正相关。
该研究强调了LCR与HBL - 3DS之间的显著关联。HBL - 3DS能够提供精确的3D面部和颈部测量,在临床环境中,它是一种对OSA患者具有潜在成本效益、无辐射且便携的筛查方法。