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肥厚性肺骨关节病——肺癌的一个被忽视的线索

Hypertrophic Pulmonary Osteoarthropathy - An Overlooked Clue of Lung Cancer.

作者信息

Kim Joshua, Hoque Farzana

机构信息

Department of Medicine Saint Louis University School of Medicine.

Department of Medicine St Louis University School of Medicine.

出版信息

J Brown Hosp Med. 2024 Jul 1;3(3):117078. doi: 10.56305/001c.117078. eCollection 2024.

DOI:10.56305/001c.117078
PMID:40026403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11864423/
Abstract

Hypertrophic osteoarthropathy (HOA) is a syndrome that presents with classic findings of digital clubbing, arthralgia, and periostosis of tubular bones. When HOA is associated with pulmonary pathologies such as lung malignancies, it is referred to as hypertrophic pulmonary osteoarthropathy (HPOA). We present a case of an elderly woman who presents with significant pain in both hands and was eventually diagnosed with lung malignancy. This case is of interest to hospital-based internists to ensure timely diagnosis of HPOA so a brief overview of the presentation, laboratory findings, and treatment of HPOA is discussed.

摘要

肥厚性骨关节病(HOA)是一种具有杵状指、关节痛和管状骨骨膜增生等典型表现的综合征。当HOA与肺部疾病如肺恶性肿瘤相关时,称为肥厚性肺骨关节病(HPOA)。我们报告一例老年女性病例,该患者双手出现明显疼痛,最终被诊断为肺恶性肿瘤。本文讨论该病例旨在引起医院内科医生对及时诊断HPOA的重视,因此简要概述了HPOA的临床表现、实验室检查结果及治疗方法。

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本文引用的文献

1
Hypertrophic osteoarthropathy.肥大性骨关节病。
Best Pract Res Clin Rheumatol. 2020 Jun;34(3):101507. doi: 10.1016/j.berh.2020.101507. Epub 2020 Apr 11.
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Hypertrophic pulmonary osteoarthropathy: an unusual presentation.肥厚性肺性骨关节病:一种不寻常的表现。
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Digital clubbing.杵状指
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Hypertrophic pulmonary osteoarthropathy as a paraneoplastic manifestation of lung cancer.肥大性肺性骨关节病作为肺癌的副瘤表现。
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