[The role of the structural characteristics of ovarian dysgerminoma in its prognosis].

The paper discusses the results of a retrospective analysis of the clinical course of ovarian dysgerminoma. The clinical and morphological peculiarities of 22 cases were evaluated. The cases were identified as "classical", unmixed dysgerminoma. Patients were divided into two study groups: (I) those with good prognosis and (2) patients with fast advancing disease. The patients of the first study group were found to have "classical" dysgerminoma, while those of the second study group revealed typical dysgerminomas with areas characteristic of tumor of the endodermal sinus, or atypical areas (a detailed morphological description of the latter is given). Some atypical areas showed structures indistinguishable between dysgerminoma and tumor of the endodermal sinus. The latter tumor was more frequent in recurrent and metastatic lesions. This makes the case for monitoring tumor process by histological examination of tumor at different stages of its progression and offers means for individually-tailored chemotherapy.