Fischl Tamara, Perucca Piero
Neuropsychiatry of Epilepsy Clinic Pediatric Neurology Outpatient Clnic Edmond and Lily-Safra Children's Hospital, Sheba Medical Center-Tel Aviv, Israel.
Epilepsy Research Centre, Department of Medicine (Austin Health), The University of Melbourne, Melbourne, Victoria, Australia.
Epilepsy Behav Rep. 2025 Feb 12;29:100727. doi: 10.1016/j.ebr.2024.100727. eCollection 2025 Mar.
Postictal psychosis (PIP) is a serious, often unrecognized complication of epilepsy. Early diagnosis and intervention can prevent life-threatening outcomes. We report the case of a 26-year-old woman with childhood-onset frontal lobe epilepsy who attempted suicide, during a postictal psychotic episode, several days after undergoing inpatient video-EEG monitoring. This case presents a real-world scenario with clear guidelines for the on-call neurologist who will need to accurately diagnose and confidently manage PIP with psychotropic medications. Moreover, this case may stimulate discussion about the complex relationship between epilepsy and psychosis.
癫痫后精神病(PIP)是癫痫一种严重且常未被识别的并发症。早期诊断和干预可预防危及生命的后果。我们报告了一名26岁患有儿童期起病的额叶癫痫的女性病例,她在接受住院视频脑电图监测几天后,在一次癫痫后精神病发作期间试图自杀。该病例呈现了一个真实场景,为值班神经科医生提供了明确的指导方针,他们需要准确诊断并自信地使用精神药物管理PIP。此外,该病例可能会引发关于癫痫与精神病之间复杂关系的讨论。