Tabatabaei Seyed Abdolhossein, Omrani Elham, Mostafavi Atoosa, Sadeghian Hakimeh, Abbasi Ali
Department of Cardiology, Dr. Shariati Hospital, Tehran University of Medical Science, Tehran, Iran.
J Cardiovasc Thorac Res. 2024;16(4):222-228. doi: 10.34172/jcvtr.33253. Epub 2024 Dec 23.
Fragmented QRS (fQRS) on a 12-lead ECG indicates electrical conduction disruption due to various cardiac issues, including coronary artery disease (CAD). This study investigated whether combining fQRS and reduced myocardial strain could predict significant CAD.
We conducted a cross-sectional study on patients with fQRS on surface ECG who underwent coronary angiography. The left ventricular strain was assessed using 2D speckle-tracking echocardiography.
We enrolled 55 patients with fQRS and significant CAD (≥70% coronary artery stenosis) and 55 control patients (≤30% stenosis). The strain was significantly reduced in segments with fQRS and significant CAD compared with the control group.
In patients with CAD, the combination of fQRS in any ECG lead and reduced strain can predict the presence and location of a coronary artery with greater than 70% stenosis.
12导联心电图上的碎裂QRS波（fQRS）表明由于各种心脏问题，包括冠状动脉疾病（CAD），导致了电传导中断。本研究调查了联合fQRS和降低的心肌应变是否能预测严重CAD。
我们对接受冠状动脉造影的体表心电图有fQRS波的患者进行了一项横断面研究。使用二维斑点追踪超声心动图评估左心室应变。
我们纳入了55例有fQRS波且患有严重CAD（冠状动脉狭窄≥70%）的患者和55例对照患者（狭窄≤30%）。与对照组相比，有fQRS波且患有严重CAD的节段应变显著降低。
在CAD患者中，任何心电图导联上的fQRS波与降低的应变相结合，可以预测狭窄大于70%的冠状动脉的存在和位置。
