Helmi Mohammad, AlJoghaiman Eman
Department of Periodontics and Community Dentistry, King Saud University, Riyadh, Riyadh Province, Saudi Arabia.
Department of preventive Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Eastern Province, Saudi Arabia.
F1000Res. 2025 Feb 6;13:1238. doi: 10.12688/f1000research.155151.2. eCollection 2024.
Hormonal changes in pregnancy and their induced effect on periodontal health are well documented. The present study is aimed at the potential repercussions of multiple pregnancies on periodontal health.
Our study utilized data from key sections of the NHANES. All the pertaining and relevant data for the study is collected. Our exposure variable was the number of pregnancies, and the outcome variable was periodontal disease. The number of pregnancies is classified as one, two, three, four, or more. Age, gender, race/ethnicity, education, poverty/income ratio, marital status, and other variables. Multiple logistic regression models were employed to assess the impact of multiple pregnancies on periodontal disease.
The crude and multiple logistic regression analyses revealed that none of the variables were significantly associated with the prevalence of periodontitis. In univariate analysis, patients with one or two pregnancies had higher odds of experiencing periodontitis (OR 1.154, 95% CI 0.748-1.779), (OR 1.464, 95% CI 0.864-2.483) respectively. However, these associations did not reach statistical significance.
Within the limitation of the study, there is no significant relationship between parity and the prevalence of periodontitis, the longitudinal study may be warranted to delve deeper into any potential associations.
孕期激素变化及其对牙周健康的诱导作用已有充分记录。本研究旨在探讨多胎妊娠对牙周健康的潜在影响。
我们的研究利用了美国国家健康与营养检查调查(NHANES)关键部分的数据。收集了该研究所有相关数据。我们的暴露变量是妊娠次数,结局变量是牙周疾病。妊娠次数分为一次、两次、三次、四次或更多次。年龄、性别、种族/民族、教育程度、贫困/收入比、婚姻状况及其他变量。采用多重逻辑回归模型评估多胎妊娠对牙周疾病的影响。
单因素和多因素逻辑回归分析显示,没有变量与牙周炎患病率显著相关。在单变量分析中,妊娠一次或两次的患者患牙周炎的几率较高(分别为OR 1.154,95%CI 0.748 - 1.779),(OR 1.464,95%CI 0.864 - 2.483)。然而,这些关联未达到统计学显著性。
在本研究的局限性范围内,产次与牙周炎患病率之间无显著关系,可能需要进行纵向研究以更深入地探究任何潜在关联。