Frimpong Paul, Mustakim Kezia Rachellea, Eo Mi Young, Amponsah Felix Ansu, Boadu Kwame Adu Okyere, Kim Soung Min
Oral and Maxillofacial Surgery and Microvascular Reconstruction LAB, Sunyani Teaching Hospital, Sunyani, Ghana.
Department of Oral and Maxillofacial Surcknogery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
J Craniofac Surg. 2025;36(5):e527-e530. doi: 10.1097/SCS.0000000000011172. Epub 2025 Mar 3.
Necrotizing fasciitis (NF) is a soft tissue infection that is primarily characterized by fast spread along the fascial planes and adjacent cutaneous tissues. Cervico-facial necrotizing fasciitis (CNF) usually presents with severe intense pain with a polymicrobial odontogenic source. Early diagnosis with aggressive management, usually involving appropriate antibiotic selection, surgical debridement, and wound care, is key to achieving a good outcome. Management of CNF requires a multidisciplinary approach and poses several challenges in resource-constrained settings, especially in developing countries. This problem is further compounded by the late presentation and uncontrolled and indiscriminate use of herbal medications in the tropics. A 65-year-old Ghanaian woman with no known comorbidity reported to the Accident and Emergency Unit of Sunyani Teaching Hospital with a chief complaint of recurrent toothache for two years and left facial swelling of 1-week duration. On physical examination, she was chronically ill, febrile (39.5 °C), and anicteric but not pale. There was a soft, fluctuant, tender swelling involving both submandibular and submental areas with increased local temperature. The swelling also extended to the anterior cervical and anterior chest walls, which were overlaid with necrotic skin. Overlying such diseased skin was also prevalent over the mammary glands. Following the clinical diagnosis of NF spread, debridement was performed, and appropriate antibiotic therapy with daily wound care management was instituted. This continued until the patient's general condition improved, and good wound healing with the formation of granulation tissue was observed. The patient was subsequently referred to a tertiary facility for skin graft. Early presentation, prompt diagnosis, and aggressive surgical and medical care are key in achieving good outcomes of NF in resource-constrained developing nations.
坏死性筋膜炎(NF)是一种软组织感染,其主要特征是沿筋膜平面和相邻皮肤组织迅速扩散。颈面部坏死性筋膜炎(CNF)通常表现为严重剧痛,源于多微生物性牙源性感染。早期诊断并积极治疗,通常包括选择合适的抗生素、手术清创和伤口护理,是取得良好治疗效果的关键。CNF的治疗需要多学科方法,在资源有限的环境中,尤其是在发展中国家,会带来诸多挑战。热带地区患者就诊延迟以及草药的无节制和滥用使这个问题更加复杂。一名65岁无已知合并症的加纳女性因反复牙痛两年、左侧面部肿胀1周,前往苏尼亚尼教学医院急诊科就诊。体格检查发现,她慢性病容,发热(39.5℃),无黄疸但面色不苍白。双侧下颌下和颏下区域有柔软、波动、压痛性肿胀,局部温度升高。肿胀还延伸至颈前和前胸壁,上面覆盖着坏死皮肤。患病皮肤在乳腺上也很常见。临床诊断为NF扩散后,进行了清创,并开始适当的抗生素治疗及每日伤口护理管理。这种治疗持续到患者一般状况改善,观察到伤口愈合良好并形成肉芽组织。患者随后被转诊至三级医疗机构进行皮肤移植。在资源有限的发展中国家,早期就诊、及时诊断以及积极的手术和医疗护理是NF取得良好治疗效果的关键。