Linna O
Acta Paediatr Scand. 1985 May;74(3):442-5. doi: 10.1111/j.1651-2227.1985.tb11000.x.
A series of 207 asthmatic children aged 4-10 years studied during the years 1976-1978 were called for a follow-up study 4-6 years later. Of these, 53 (26%) children were completely symptom-free and 154 still had symptoms. The proportion of symptom-free patients was highest (45%) among those having attacks only during respiratory infections. The prognosis was worsened by such factors as a high rate of attacks, an association with eczema and a history of otitis media or adenoidectomy. The clinical picture of disease among children having attacks only during respiratory infections (wheezy bronchitis) was distinctive from that in asthma and may be separated as its own entity. Subgrouping of childhood asthma is beneficial for a clinician when considering the intensity of therapy or the need for controls.
对1976年至1978年间研究的207名4至10岁哮喘儿童进行了随访,随访时间为4至6年后。其中,53名(26%)儿童完全无症状,154名仍有症状。仅在呼吸道感染时发作的患者中无症状患者比例最高(45%)。发作频率高、合并湿疹以及有中耳炎或腺样体切除术病史等因素会使预后恶化。仅在呼吸道感染时发作的儿童(喘息性支气管炎)的疾病临床表现与哮喘不同,可作为一个独立的病种区分开来。儿童哮喘的亚组分类对临床医生在考虑治疗强度或控制需求时是有益的。