Sommer J R, Scherer B
Am J Physiol. 1985 Jun;248(6 Pt 2):H792-803. doi: 10.1152/ajpheart.1985.248.6.H792.
A strand each of cardiac conduction and working cells of the left ventricle is studied in serial sections with the light microscope to define the geometry of cell appositions that form networks of cardiac muscle cells. Anatomic and thus electrical coupling is very frequent among all cells; it is accomplished within a few hundred micrometers axially regardless at which point of the strand electrical current is assumed to originate. Most individual cardiac myocytes are not only connected in longitudinal direction but also make lateral contacts. Only a few bundles of varying diameters remain unconnected over appreciable distances of greater than 200 micron (so-called unit bundles). Thus abnormal current vectors are averted, at least in normal cardiac tissue, even if excitation were to originate from a point. Plastic thick sections studied with the light microscope were unsuitable to define cell lengths.
在光学显微镜下，对左心室的心脏传导细胞和工作细胞各一条束进行连续切片研究，以确定形成心肌细胞网络的细胞并列结构的几何形状。在所有细胞中，解剖学上以及因此电学上的耦合非常频繁；无论假设电流从束的哪个点起源，它都在轴向几百微米内完成。大多数单个心肌细胞不仅在纵向相连，而且还形成横向接触。只有少数几束不同直径的纤维在超过200微米的可观距离内保持不相连（所谓的单位束）。因此，至少在正常心脏组织中，即使兴奋起源于一点，异常电流向量也会避免。用光学显微镜研究的塑料厚切片不适用于确定细胞长度。
