Suppr超能文献

孕产妇抑郁在种族差异和出生体重中的作用。

The Role of Maternal Depression in Racial Disparities and Birth Weight.

作者信息

Eitel Anna E, Witcraft Sara M, Cortese Bernadette, Sujan Ayesha C, King Courtney, Guille Constance

机构信息

College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.

出版信息

J Racial Ethn Health Disparities. 2025 Mar 4. doi: 10.1007/s40615-025-02359-z.

Abstract

INTRODUCTION

Pregnant people experiencing major depression during pregnancy are at increased risk for premature labor and infants with low birth weight, and there are significant racial disparities in these outcomes. Black women are at higher risk for having premature and low birth weight infants relative to their White counterparts. As such, we sought to examine the relationships between race, depression, and obstetric outcomes (low birth weight and prematurity) in both Black and White women with live births.

METHODS

This study included 185 pregnant women receiving behavioral health services within an Ob/Gyn clinic in an academic medical center in South Carolina. Main and interactive effects on birth weight and gestational age were evaluated with analysis of covariance controlling for maternal age.

RESULTS

The association between race and low birth weight was driven primarily by maternal depression. Infants of depressed Black women had significantly reduced birth weight relative to infants of depressed White women, but there was no evidence of racial disparities in birth weight among non-depressed Black women compared to non-depressed White women. Depression symptom severity was not associated with birth outcomes, and there was no effect of depression or race on prematurity.

CONCLUSION

The occurrence of depression during pregnancy may in part account for racial disparities in infant birth weight. Interventions to reduce depression across birthing persons but especially among Black women may be a promising direction to address racial disparities in low birth weight.

摘要

引言

孕期经历重度抑郁的孕妇早产及分娩低体重儿的风险增加,且这些结果存在显著的种族差异。与白人女性相比,黑人女性分娩早产及低体重儿的风险更高。因此,我们试图研究有活产经历的黑人和白人女性中种族、抑郁与产科结局(低体重和早产)之间的关系。

方法

本研究纳入了南卡罗来纳州一家学术医疗中心妇产科诊所内接受行为健康服务的185名孕妇。通过协方差分析控制产妇年龄,评估对出生体重和孕周的主要及交互效应。

结果

种族与低体重之间的关联主要由产妇抑郁驱动。与抑郁白人女性的婴儿相比,抑郁黑人女性的婴儿出生体重显著降低,但与非抑郁白人女性相比,非抑郁黑人女性在出生体重方面没有种族差异的证据。抑郁症状严重程度与出生结局无关,抑郁或种族对早产没有影响。

结论

孕期抑郁的发生可能部分解释了婴儿出生体重的种族差异。针对所有分娩者尤其是黑人女性减少抑郁的干预措施,可能是解决低体重种族差异的一个有前景的方向。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验