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Improvement in dermatomyositis-associated muscle disease with anifrolumab.

作者信息

Shayegan Leila H, Shaw Katharina S, Wieschhoff Ged G, Ezeh Nnenna, Kim Yoo Jung, Shahriari Neda, Anshelevich Ellen E, Acevedo Lorena A, LaChance Avery, Dedeoglu Fatma, Castillo Rochelle L, Ho Allen W, Vleugels Ruth Ann

机构信息

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Dermatology Program, Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

出版信息

Br J Dermatol. 2025 May 19;192(6):1126-1128. doi: 10.1093/bjd/ljaf064.

DOI:10.1093/bjd/ljaf064
PMID:40036364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12107708/
Abstract
摘要

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3
Elevated type I IFN signalling directly affects CD8 T-cell distribution and autoantigen recognition of the skeletal muscles in active JDM patients.活性 JDM 患者中 I 型干扰素信号的上调直接影响 CD8 T 细胞在骨骼肌中的分布和自身抗原识别。
J Autoimmun. 2024 Jun;146:103232. doi: 10.1016/j.jaut.2024.103232. Epub 2024 Apr 30.
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Dermatomyositis and type 1 interferons.皮肌炎与 1 型干扰素。
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