Bloomfield S E, Gray G F
Ann Ophthalmol. 1979 Nov;11(11):1783-6.
Endothelial pigmentation does not usually interfere with vision. This case report documents a dense and extensive deposition of uveal pigment in corneal endothelial cells of a patient who had undergone 2 previous grafts subsequent to an alkali burn injury. The previous graft in which the pigmentation occurred remained compensated, but vision was impaired secondary to dense endothelial pigmentation. A combination of the initial chemical injury, recurrent iritis, chronic glaucoma, and multiple intraocular procedures may have resulted in the stimulus for the uveal tract to disperse a large amount of pigment onto the cornea and its subsequent phagocytosis by the endothelium. Endothelial pigmentation may become a more commonly seen complication in attempts to treat the severely damaged anterior segment.
内皮色素沉着通常不会影响视力。本病例报告记录了一名在碱烧伤后接受过两次移植手术的患者，其角膜内皮细胞中出现了密集且广泛的葡萄膜色素沉着。色素沉着发生的前一次移植仍保持代偿状态，但由于内皮色素沉着密集，视力受到损害。最初的化学损伤、复发性虹膜炎、慢性青光眼以及多次眼内手术的综合作用，可能促使葡萄膜将大量色素散布到角膜上，随后被内皮细胞吞噬。在治疗严重受损的眼前节时，内皮色素沉着可能会成为一种更常见的并发症。
