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澳大利亚一家地区医院中外观相似、发音相似药物的围手术期事件:使用新型药物安全文化评估工具进行评估

Look-alike, sound-alike medication perioperative incidents in a regional Australian hospital: assessment using a novel medication safety culture assessment tool.

作者信息

Ryan Alexandra N, Robertson Kelvin L, Glass Beverley D

机构信息

Pharmacy Department, Townsville University Hospital, 100 Angus Smith Drive, Douglas, Queensland 4814, Australia.

College of Medicine & Dentistry, James Cook University, 1 James Cook Drive, Douglas, Queensland 4811, Australia.

出版信息

Int J Qual Health Care. 2025 Mar 25;37(1). doi: 10.1093/intqhc/mzaf018.

Abstract

BACKGROUND

Medication safety remains a global concern, with governments and organizations striving to mitigate preventable patient harm across healthcare systems. Look-alike, sound-alike medication incidents and the safety culture are widely acknowledged as a contributor to medication errors, particularly within the high-risk perioperative environment. The Medication Safety Culture Indicator Matrix (MedSCIM) is a novel tool developed by the Canadian Institute for Safe Medication Practices to assess the maturity of the medication safety culture. This study aims to delineate look-alike sound-alike (LASA) medication incidents reported in the pharmacy and perioperative settings of an Australian hospital and assess the maturity of the medication safety culture.

METHODS

The study setting is within a large regional hospital in Australia, servicing both adult and paediatric populations. Medication incidents from 1 April 2018 to 1 April 2023 were retrospectively gathered from the Clinical Incident Management System, Riskman®. Data and statistical analyses were carried out using Microsoft Excel®. The necessary approvals were secured from the Heath Service Human Research and Ethics Committee.

RESULTS

During the 5-year period, a total of 246 (4.1%) of the 6002 medication incidents within the health service were identified as meeting the inclusion criteria. Of the 246 medication incidents, 63.0% were identified from the Pharmacy Department, while 22.0% and 15.0% were from the Post Anaesthetic Care Unit and Anaesthetics Department, respectively. The most frequently reported incident classification in both the Anaesthetics Department and Post Anaesthetic Care Unit was 'incorrect dose', followed by 'incorrect medication'. Throughout the 5-year period, 46 (18.7%) of the 246 medication incidents were attributed to look-alike, sound-alike sources of error, predominantly identified in the Pharmacy Department (73.9%), followed by the Anaesthetics Department (17.4%) and the Post Anaesthetic Care Unit (8.7%). High-risk medications were most frequently reported to the Anaesthetics Department. Packaging (packaging alone, naming and packaging, and syringe swaps) was determined to be a contributing factor in 30 (65.2%) of the 46 LASA medication incidents. MedSCIM assessment revealed a reactive medication safety culture. Additionally, the medication incident report documentation was found to be mostly complete or semi-complete.

CONCLUSION

Our analysis delineated medication incidents occurring across the entire medication management cycle and identified incidents related to LASA medications as a contributor to medication incidents across these clinical settings. This novel medication safety culture tool assessment highlighted opportunities for improvement with clinical incident documentation.

摘要

背景

用药安全仍是全球关注的问题,各国政府和组织都在努力减少医疗系统中可预防的患者伤害。外观相似、发音相似的用药事件和安全文化被广泛认为是用药错误的一个原因,尤其是在高风险的围手术期环境中。用药安全文化指标矩阵(MedSCIM)是加拿大安全用药实践研究所开发的一种新型工具,用于评估用药安全文化的成熟度。本研究旨在描述澳大利亚一家医院药房和围手术期环境中报告的外观相似、发音相似(LASA)用药事件,并评估用药安全文化的成熟度。

方法

研究地点在澳大利亚一家大型地区医院,服务于成人和儿童患者。回顾性收集了2018年4月1日至2023年4月1日期间临床事件管理系统Riskman®中的用药事件。使用Microsoft Excel®进行数据和统计分析。已获得卫生服务人类研究与伦理委员会的必要批准。

结果

在这5年期间,卫生服务机构6002起用药事件中共有246起(4.1%)被确定符合纳入标准。在这246起用药事件中,63.0%是从药房发现的,而分别有22.0%和15.0%来自麻醉后护理病房和麻醉科。麻醉科和麻醉后护理病房最常报告的事件分类是“剂量错误”,其次是“用药错误”。在整个5年期间,246起用药事件中有46起(18.7%)归因于外观相似、发音相似的错误来源,主要在药房发现(73.9%),其次是麻醉科(17.4%)和麻醉后护理病房(8.7%)。高风险药物最常报告给麻醉科。在46起LASA用药事件中,有30起(65.2%)确定包装(仅包装、命名和包装以及注射器更换)是一个促成因素。MedSCIM评估显示用药安全文化具有反应性。此外,用药事件报告文件大多是完整或半完整的。

结论

我们的分析描述了整个用药管理周期中发生的用药事件,并确定与LASA药物相关的事件是这些临床环境中用药事件的一个原因。这种新型用药安全文化工具评估突出了临床事件文件记录方面的改进机会。

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本文引用的文献

1
Look-alike medications in the perioperative setting: scoping review of medication incidents and risk reduction interventions.
Int J Clin Pharm. 2024 Feb;46(1):26-39. doi: 10.1007/s11096-023-01629-2. Epub 2023 Sep 9.
2
3
The problem of look-alike, sound-alike name errors: Drivers and solutions.
Br J Clin Pharmacol. 2021 Feb;87(2):386-394. doi: 10.1111/bcp.14285. Epub 2020 Apr 20.
5
The contribution of labelling to safe medication administration in anaesthetic practice.
Best Pract Res Clin Anaesthesiol. 2011 Jun;25(2):145-59. doi: 10.1016/j.bpa.2011.02.009.
7
Reporting of adverse events.
N Engl J Med. 2002 Nov 14;347(20):1633-8. doi: 10.1056/NEJMNEJMhpr011493.
8
Why error reporting systems should be voluntary.
BMJ. 2000 Mar 18;320(7237):728-9. doi: 10.1136/bmj.320.7237.728.

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