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基于匈牙利真实世界医疗保险理赔数据的女性不孕症流行病学疾病负担及全国年度医疗保险治疗费用

Epidemiological disease burden and annual, nationwide health insurance treatment cost of female infertility based on real-world health insurance claims data in Hungary.

作者信息

Pónusz-Kovács Dalma, Csákvári Tímea, Sántics-Kajos Luca Fanni, Elmer Diána, Pónusz Róbert, Kovács Bettina, Várnagy Ákos, Kovács Kálmán, Bódis József, Boncz Imre

机构信息

Faculty of Health Sciences, Institute for Health Insurance, University of Pécs, 7621 Vörösmarty Utca 3, Pécs, Hungary.

National Laboratory On Human Reproduction, University of Pécs, 7624 Ifjúság Utca 20, Pécs, Hungary.

出版信息

BMC Health Serv Res. 2025 Mar 4;25(1):336. doi: 10.1186/s12913-025-12348-x.

DOI:10.1186/s12913-025-12348-x
PMID:40038705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11881250/
Abstract

BACKGROUND

Infertility affects more than 50 million couples worldwide, resulting in a significant burden on individuals and society. Its prevalence ranges from 8-12% among developed countries. The growing number of patients poses an increasing challenge to the healthcare system and its funding. Our quantitative, descriptive, and cross-sectional study aimed to analyze the prevalence and annual nationwide health insurance treatment cost of female infertility in Hungary in 2019.

METHODS

We used claims data obtained from the Hungarian National Health Insurance Fund Administration (NHFIA). The number of patients, total and age-specific prevalence, annual health insurance expenditure, and the distribution of costs by age group were evaluated. Infertility was determined according to the World Health Organization International Classification of Diseases codes (N.97.0, N97.1, N97.2, N97.3, N97.4, N97.8, and N97.9) and the utilization of each healthcare service type. During the study descriptive statistics, correlation analysis and t-test were used.

RESULTS

In 2019, the NHIFA spent a total of 7.2 billion HUF (22.2 million EUR) on female infertility treatment in Hungary (33,151 women in outpatient care). The most significant costs were related to inpatient care (4.1 billion HUF, 12.7 million EUR). The highest number of patients and prevalence (650.4 per 100,000 women) were found in outpatient care. In inpatient care, the prevalence is substantially lower (206.7 per 100,000 women). Regardless of its type, female infertility mainly affects patients in the 30-39 years age group (number of patients: 18,156 women). The average annual health insurance expenditure per capita was 1,083 EUR.

CONCLUSIONS

Reproductive health education, prevention, and medical screening play inevitable roles in the early stages of reproductive life to reduce the risk of infertility and decrease treatment costs.

摘要

背景

不孕症影响着全球超过5000万对夫妇,给个人和社会带来了沉重负担。在发达国家,其患病率在8%至12%之间。患者数量的不断增加给医疗保健系统及其资金带来了日益严峻的挑战。我们的定量、描述性横断面研究旨在分析2019年匈牙利女性不孕症的患病率和全国年度医疗保险治疗费用。

方法

我们使用了从匈牙利国家健康保险基金管理局(NHFIA)获得的理赔数据。评估了患者数量、总体患病率和特定年龄患病率、年度医疗保险支出以及按年龄组划分的费用分布。根据世界卫生组织国际疾病分类代码(N.97.0、N97.1、N97.2、N97.3、N97.4、N97.8和N97.9)以及每种医疗服务类型的使用情况来确定不孕症。在研究过程中使用了描述性统计、相关性分析和t检验。

结果

2019年,匈牙利国家健康保险基金管理局在女性不孕症治疗上总共花费了72亿匈牙利福林(2220万欧元)(门诊治疗的女性患者有33151人)。最主要的费用与住院治疗有关(41亿匈牙利福林,1270万欧元)。门诊治疗中患者数量和患病率最高(每10万名女性中有650.4人)。在住院治疗中,患病率则低得多(每10万名女性中有206.7人)。无论治疗类型如何,女性不孕症主要影响30至39岁年龄组的患者(患者数量:18156名女性)。人均年度医疗保险支出为1083欧元。

结论

生殖健康教育、预防和医学筛查在生殖生命的早期阶段起着不可或缺的作用,以降低不孕风险并减少治疗费用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/f36ac5804b45/12913_2025_12348_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/7f73176a8409/12913_2025_12348_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/923fa3dada7e/12913_2025_12348_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/f36ac5804b45/12913_2025_12348_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/7f73176a8409/12913_2025_12348_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/923fa3dada7e/12913_2025_12348_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc00/11881250/f36ac5804b45/12913_2025_12348_Fig3_HTML.jpg

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