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[生物活性物质作用下网状内皮细胞组织蛋白酶活性的变化]

[Changes in the cathepsin activity of reticuloendothelial cells under the effect of biologically active substances].

作者信息

Popova G O, Sadovskaia L Ia, Mikhalevich R V, Mishankin B N, Makarovskaia L N

出版信息

Antibiot Med Biotekhnol. 1985 Feb;30(2):106-9.

PMID:4004183
Abstract

The level of cathepsin D, an enzyme of the lysosomal origin was used as a criterion of the increase in the digestive capacity of macrophages under the action of biologically active substances. It was shown that the use of prodigiosan changed the enzyme activity in the cells of the peritoneal exudate and spleen of the albino mice. Increased activity of cathepsin D was considered as a state of increased readiness for phagocytosis.

摘要

组织蛋白酶D是一种溶酶体来源的酶,其水平被用作衡量生物活性物质作用下巨噬细胞消化能力增强的标准。结果表明,使用灵菌红素可改变白化小鼠腹膜渗出液和脾脏细胞中的酶活性。组织蛋白酶D活性的增加被认为是吞噬作用准备状态增强的一种状态。

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