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蝎子(五条纹肥尾蝎)毒液对葡萄糖-6-磷酸脱氢酶活性的抑制作用。

Inhibition of glucose-6-phosphate dehydrogenase activity by scorpion Leiurus quinquestriatus (H and E) venom.

作者信息

Rabie F, Halim N, Karrar O, Ibrahim S A

出版信息

J Trop Med Hyg. 1979 May;82(5):102-4.

PMID:40042
Abstract

Crystalline glucose-6-phosphate dehydrogenase was significantly inhibited by L-quinquestriatus venom. Neither boiling nor dialysis could abolish this inhibition completely. Raising the concentration of either G6P or NADP in the reaction mixture reversed the inhibition, indicating that the latter was competitive with respect to the substrate and the coenzyme.

摘要

结晶葡萄糖-6-磷酸脱氢酶受到五步蛇毒的显著抑制。煮沸或透析都不能完全消除这种抑制作用。提高反应混合物中G6P或NADP的浓度可逆转这种抑制作用,这表明后者在底物和辅酶方面具有竞争性。

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Proceedings: Lipids in scorpion (Leiurus quinquestriatus H and E) venom.
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