Huizinga Famke, Westerink Nico-Derk L, Walenkamp Annemiek Me, Berendsen Annette J, de Greef Mathieu Hg, de Boer Michiel R, de Bock Geertruida H, Berger Marjolein Y, Brandenbarg Daan
Department of Primary and Long-term Care, University Medical Center Groningen, University of Groningen, Groningen.
Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen.
Br J Gen Pract. 2025 May 2;75(754):e366-e374. doi: 10.3399/BJGP.2024.0558. Print 2025 May.
Physical activity (PA) benefits cancer survivors' health, yet no PA programmes are incorporated in Dutch general practice.
To evaluate cancer survivors' outcomes following a PA programme in general practice.
A single-arm PA intervention implementation study among cancer survivors in 15 Dutch general practices.
Patients aged ≥18 years who completed primary cancer treatment ≥6 months prior were eligible. The 9-month intervention comprised counselling sessions with a primary care practitioner (PCP) aimed at increasing daily PA. Reach, Effectiveness, and Implementation of the RE-AIM framework were evaluated among participants. Primary health outcomes included self-reported symptoms of fatigue, depression, and anxiety; secondary outcomes included step count, caloric expenditure, weight, physical function, self-reported quality of life, and PA. Outcomes were assessed at time (T)-T (0, 3, 6, and 9 months) or at PCPs' sessions S1-S6 (0, 3, 6 weeks, and 3, 6, 9 months). Non-participants completed a single baseline questionnaire. The study used (non-)parametric independent tests and linear mixed models for analyses.
Of 564 invited patients, 149 (26%) participated. Participants had less formal education, higher unemployment, less PA, and more fatigue and psychological symptoms than non-participants. All primary and most secondary health outcomes improved over time, with clinically relevant changes in step count and physical function. In total, 11% ( = 16/149) dropped out before and 26% ( = 35/133) during the programme. Counselling session adherence and PA goal achievement were 98% ( = 647/661) and 73% ( = 81/111), respectively.
The programme reached long-term cancer survivors with poorer health status, and showed positive health changes particularly on PA and physical function. Such PA programmes may benefit the health of a rising number of cancer survivors visiting primary care.
体育活动有益于癌症幸存者的健康，但荷兰的普通医疗实践中并未纳入任何体育活动计划。
评估普通医疗实践中一项体育活动计划对癌症幸存者的效果。
在15家荷兰普通医疗实践机构中针对癌症幸存者开展的单组体育活动干预实施研究。
年龄≥18岁且在至少6个月前完成原发性癌症治疗的患者符合条件。为期9个月的干预包括与初级保健医生（PCP）进行咨询会议，旨在增加日常体育活动量。在参与者中评估了RE-AIM框架的覆盖范围、有效性和实施情况。主要健康结局包括自我报告的疲劳、抑郁和焦虑症状；次要结局包括步数、热量消耗、体重、身体功能、自我报告的生活质量和体育活动量。结局在时间点（T）——T（0、3、6和9个月）或在初级保健医生的会诊S1-S6（0、3、6周以及3、6、9个月）时进行评估。未参与者完成一份单一的基线问卷。该研究使用（非）参数独立检验和线性混合模型进行分析。
在564名受邀患者中，149名（26%）参与。与未参与者相比，参与者受正规教育程度较低、失业率较高、体育活动量较少，且疲劳和心理症状较多。所有主要健康结局和大多数次要健康结局随时间推移均有所改善，步数和身体功能有临床相关变化。总共有11%（=16/149）在计划开始前退出，26%（=35/133）在计划期间退出。咨询会议的依从率和体育活动目标达成率分别为98%（=647/661）和73%（=81/111）。
该计划覆盖了健康状况较差的长期癌症幸存者，并显示出对健康有积极变化，特别是在体育活动和身体功能方面。此类体育活动计划可能有益于越来越多前往初级保健机构就诊的癌症幸存者的健康。
