Sapritskiĭ A V
Arkh Patol. 1985;47(3):33-8.
Morphometry of lymphocytic infiltration of bladder tumour parenchyma was performed. In human bladder tumours, the positive correlation between the number of intraepithelial lymphocytes and stages of tumour progression was found. The same correlation between the degree of lymphocytic infiltration of tumour parenchyma and the rate of tumour cell proliferation was observed when historadioautographs of experimental rat bladder neoplasms were analysed. The lack of tumour cell degeneration and necrosis in the areas of intraepithelial lymphocyte accumulation and the presence of these processes in lymphocytes were noted. The data obtained give a new insight into the role of lymphocytes in tumours and confirm, although indirectly, the ability of lymphocytes to maintain or stimulate tumour growth.
对膀胱肿瘤实质的淋巴细胞浸润进行了形态测量。在人类膀胱肿瘤中，发现上皮内淋巴细胞数量与肿瘤进展阶段之间存在正相关。在分析实验大鼠膀胱肿瘤的组织放射自显影片时，观察到肿瘤实质的淋巴细胞浸润程度与肿瘤细胞增殖速率之间也存在同样的相关性。注意到上皮内淋巴细胞聚集区域缺乏肿瘤细胞变性和坏死，而在淋巴细胞中存在这些过程。所获得的数据为淋巴细胞在肿瘤中的作用提供了新的见解，并间接证实了淋巴细胞维持或刺激肿瘤生长的能力。
