Kobaidze Ketino, Wiley Zanthia
Department of Medicine, Division of Hospital Medicine Emory University School of Medicine, Atlanta, GA, USA.
Department of Medicine, Division of Infectious Diseases Emory University School of Medicine, Atlanta, GA, USA.
Brown J Hosp Med. 2023 Mar 1;2(2):72707. doi: 10.56305/001c.72707. eCollection 2023.
Botulism is a potentially deadly neuroparalytic disease that affects all age groups; it is highly challenging to diagnose due to its nonspecific symptoms. Infant botulism is the most common form of botulism in the United States, followed by foodborne and wound botulism. Since most patients require hospitalization, it is imperative that both adult and pediatric physicians recognize its symptoms. Patients with severe forms of botulism typically present early after toxin ingestion and progress rapidly. Although rare in the United States, botulism remains a public health concern since even one case may predict an outbreak. This review summarizes the typical clinical course of botulism and recommendations for diagnosis and management.
肉毒中毒是一种可能致命的神经麻痹性疾病,可影响所有年龄组;因其症状不具特异性,故诊断极具挑战性。婴儿肉毒中毒是美国最常见的肉毒中毒形式,其次是食源性和创伤性肉毒中毒。由于大多数患者需要住院治疗,成年和儿科医生都必须认识到其症状。严重形式的肉毒中毒患者通常在摄入毒素后早期发病,并迅速进展。尽管在美国罕见,但肉毒中毒仍是一个公共卫生问题,因为即使出现一例病例也可能预示着一次暴发。本综述总结了肉毒中毒的典型临床病程以及诊断和管理建议。