Borman Pim T S, Uijtewaal Prescilla, Snyder Jeffrey, Allen Bryan, Atienza Caiden K, Woodhead Peter, Hyer Daniel E, Raaymakers Bas W, Fast Martin F
Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.
Department of Radiation Oncology, Yale New Haven Health, New Haven, CT, USA.
Phys Imaging Radiat Oncol. 2025 Feb 15;33:100729. doi: 10.1016/j.phro.2025.100729. eCollection 2025 Jan.
Intensity-modulated radiotherapy (IMRT) in combination with magnetic resonance imaging (MRI)-guided gated delivery represents the latest development in the treatment of abdominothoracic tumours on MR-linac. In contrast, volumetric-modulated arc therapy (VMAT) is typically used on conventional linacs due to its superior delivery efficiency and speed. Non-inferior VMAT plans were created in a research treatment planning system for eight lung cancer patients previously treated on an MR-linac. VMAT plans were delivered on a moving dosimeter using respiratory multi-leaf collimator (MLC) tracking. VMAT with MLC tracking achieved an average 2%/2 mm local gamma pass rate of 93% relative to planned dose with a delivery efficiency of 83%.
调强放射治疗（IMRT）与磁共振成像（MRI）引导的门控输送相结合，代表了MR直线加速器治疗腹胸肿瘤的最新进展。相比之下，容积调强弧形治疗（VMAT）由于其卓越的输送效率和速度，通常用于传统直线加速器。在一个研究治疗计划系统中，为先前在MR直线加速器上接受治疗的8例肺癌患者创建了非劣效VMAT计划。使用呼吸多叶准直器（MLC）跟踪在移动剂量仪上实施VMAT计划。采用MLC跟踪的VMAT相对于计划剂量的平均局部γ通过率为2%/2 mm时达到93%，输送效率为83%。
