Cao Xinyu, Zhang Huanhuan, Li Yi, Liu Meinv, He Jinhua, Li Jianli
Department of Anesthesiology, Hebei General Hospital, Shijiazhuang, China.
Graduate School of Hebei Medical University, Shijiazhuang, China.
Geriatr Gerontol Int. 2025 Apr;25(4):565-571. doi: 10.1111/ggi.70023. Epub 2025 Mar 6.
This study aimed to investigate the predictive effect of hemoglobin to red cell distribution width ratio (HRR) on postoperative delirium (POD) in older patients undergoing hip fracture surgery.
POD was diagnosed by capturing descriptive words from the medical records. The correlation between POD and HRR was determined using logistic regression analysis, and the receiver operating characteristic curve was used to further evaluate the value of HRR in predicting POD.
In total, 202 older patients accepting hip fracture surgery were included in our study. The result of multiple logistic regression analysis presented HRR (odds ratio, 0.504 [95% confidence interval, 0.340-0.747]; P < 0.001), American Society of Anesthesiologists physical status >2, and neutrophils were independently correlated with POD. The area under the curve of HRR was 0.746 (95% confidence interval, 0.676-0.815), and the optimal cutoff value was 8.322.
HRR, American Society of Anesthesiologists physical status >2 and neutrophils could independently predict POD in older patients undergoing hip fracture surgery, and HRR had satisfactory predictive value. However, further research is needed to confirm our findings. Geriatr Gerontol Int 2025; 25: 565-571.
本研究旨在探讨血红蛋白与红细胞分布宽度比值（HRR）对老年髋部骨折手术患者术后谵妄（POD）的预测作用。
通过从病历中提取描述性词汇来诊断POD。采用逻辑回归分析确定POD与HRR之间的相关性，并使用受试者工作特征曲线进一步评估HRR在预测POD方面的价值。
本研究共纳入202例接受髋部骨折手术的老年患者。多元逻辑回归分析结果显示，HRR（比值比，0.504[95%置信区间，0.340 - 0.747]；P < 0.001）、美国麻醉医师协会身体状况>2以及中性粒细胞与POD独立相关。HRR的曲线下面积为0.746（95%置信区间，0.676 - 0.815），最佳截断值为8.322。
HRR、美国麻醉医师协会身体状况>2以及中性粒细胞可独立预测老年髋部骨折手术患者的POD，且HRR具有令人满意的预测价值。然而，需要进一步研究来证实我们的发现。《老年医学与老年病学国际杂志》2025年；25：565 - 571。
