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鸡胸矫治器取出术后抗生素使用与手术部位感染的相关性

Association of Antibiotic Use and Surgical Site Infection Following Pectus Bar Removal.

作者信息

Scaife Jack H, Clinker Christopher E, Wallace Marshall W, Eldredge R Scott, Lee Justin, Russell Katie W

机构信息

University of Utah School of Medicine, Salt Lake City, Utah.

University of Utah School of Medicine, Salt Lake City, Utah.

出版信息

J Surg Res. 2025 Mar;307:184-188. doi: 10.1016/j.jss.2025.01.013. Epub 2025 Mar 5.

Abstract

INTRODUCTION

Surgical site infection (SSI) following pectus bar removal (PBR) is one of the most common complications despite being a clean procedure. The effect of preoperative antibiotic use on SSI rates has not been well-studied. This study aimed to evaluate the association of preoperative antibiotic use on SSIs following PBR. We hypothesized that patients who received preoperative antibiotics would have lower SSI rates.

METHODS

A retrospective review was conducted of pediatric patients who underwent PBR from January 2018 to July 2023 at a single center. Patient demographic data, preoperative antibiotic administration, and a 30-d postoperative clinical course were collected. SSI was defined as a documented infection adjacent to the surgical incision requiring antibiotics or operative intervention within 30 ds of surgery.

RESULTS

There were 198 patients in the cohort. The majority were male (81%), with a median age of 18. Postpectus bar removal SSI was documented in 2% (4/198) of patients, with any complications occurring in 6% of the cohort. Despite being a clean case, 67% received preoperative antibiotics. There was no statistical difference between SSIs in patients who received preoperative antibiotics versus those who did not (0.8% versus 4.6%, P = 0.10).

CONCLUSIONS

Following PBR, close to 5% of patients had a documented SSI when antibiotics were not part of routine preoperative care. While we did not find a significant difference in SSI with antibiotic use, the incidence of SSI is higher than in other clean wound class procedures. Further efforts are needed to identify risk factors of SSI following PBR.

摘要

引言

尽管鸡胸矫治器取出术(PBR)属于清洁手术,但术后手术部位感染(SSI)却是最常见的并发症之一。术前使用抗生素对SSI发生率的影响尚未得到充分研究。本研究旨在评估术前使用抗生素与鸡胸矫治器取出术后SSI之间的关联。我们假设接受术前抗生素治疗的患者SSI发生率会更低。

方法

对2018年1月至2023年7月在单一中心接受鸡胸矫治器取出术的儿科患者进行回顾性研究。收集患者的人口统计学数据、术前抗生素使用情况以及术后30天的临床病程。SSI定义为手术切口附近有记录的感染,需要在术后30天内使用抗生素或进行手术干预。

结果

该队列中有198例患者。大多数为男性(81%),中位年龄为18岁。鸡胸矫治器取出术后有2%(4/198)的患者发生了SSI,该队列中有6%的患者出现了任何并发症。尽管该手术属于清洁手术,但67%的患者接受了术前抗生素治疗。接受术前抗生素治疗的患者与未接受术前抗生素治疗的患者之间的SSI发生率无统计学差异(0.8%对4.6%,P = 0.10)。

结论

鸡胸矫治器取出术后,在抗生素不作为常规术前护理一部分的情况下,近5%的患者有记录的SSI。虽然我们未发现使用抗生素的患者与未使用抗生素的患者在SSI方面存在显著差异,但SSI的发生率高于其他清洁伤口类手术。需要进一步努力确定鸡胸矫治器取出术后SSI的危险因素。

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